Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | KDM4A | O75164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | CNR1 | P21554 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10695728 | 0.82 | MAPT (0.39) | MAPTALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10695201 | 0.81 | SCN9A (0.35) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10693758 | 0.74 | AURKA (0.41) | MAPTALDH1A1MEN1KMT2AKDM4A | |
| SCHEMBL10696397 | 0.73 | ALDH1A1 (0.40) | MAPTALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10695367 | 0.72 | KDM4E (0.42) | MAPTALDH1A1MEN1KMT2AKDM4E | |
| SCHEMBL10695087 | 0.72 | TNKS2 (0.44) | MAPTALDH1A1MEN1KMT2AL3MBTL1 | |
| SCHEMBL10701189 | 0.72 | HSD17B10 (0.41) | MAPTALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10695666 | 0.71 | CREBBP (0.40) | MAPTMEN1KMT2AGAACREBBP | |
| SCHEMBL10698241 | 0.71 | ADORA2B (0.34) | MAPTALDH1A1MEN1KMT2AHSD17B10 | |
| SCHEMBL10693698 | 0.70 | KDM4E (0.40) | ALDH1A1HSD17B10KDM4ESCN9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0268178-A1 | Pyrrolo-benzimidazoles, medicaments containing these compounds and process for their preparation | Dr. Karl Thomae GmbH (DE) | 1988-05-25 | — | — | EP | disclosed |