Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 2/20 | 0.45 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
| ▸ | SCN1A | P35498 | 1/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.44 |
| ▸ | SRC | P12931 | 2/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10698677 | 0.88 | GABRA1 (0.56) | HTR2ALMNAFGFR1SRCPPARG | |
| SCHEMBL10694618 | 0.83 | GABRA1 (0.56) | HTR2ALMNAPPARGNPC1RAB9A | |
| SCHEMBL10691138 | 0.80 | GABRA1 (0.49) | ALDH1A1HTR2AKCNH2LMNA | |
| SCHEMBL10691683 | 0.76 | HPGD (0.44) | ALDH1A1LMNA | |
| SCHEMBL11832211 | 0.74 | GABRA5 (0.51) | KCNH2LMNA | |
| SCHEMBL11826946 | 0.74 | GABRA1 (0.69) | ALDH1A1CHRM1KCNH2LMNARAB9A | |
| SCHEMBL11809246 | 0.74 | OPRK1 (0.69) | HTR2AKCNH2LMNAADORA3 | |
| SCHEMBL11826392 | 0.73 | GABRA1 (0.59) | KCNH2LMNA | |
| SCHEMBL10693440 | 0.72 | GABRA1 (0.60) | ALDH1A1HTR2ALMNANPC1 | |
| SCHEMBL11835751 | 0.72 | GABRA1 (0.49) | CHRM1HTR2AKCNH2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0255028-A2 | 1,4-Benzodiazepines, their preparation and use as PAF antagonists | BOEHRINGER INGELHEIM KG (DE) | 1988-02-03 | — | — | EP | disclosed |