Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.61 |
| ▸ | LPAR1 | Q92633 | 9/20 | 0.61 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.61 |
| ▸ | LPAR6 | P43657 | 3/20 | 0.61 |
| ▸ | LPAR4 | Q99677 | 3/20 | 0.61 |
| ▸ | LPAR5 | Q9H1C0 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CNR1 | P21554 | 1/20 | 0.45 |
| ▸ | CNR2 | P34972 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.43 |
| ▸ | PRKCG | P05129 | 1/20 | 0.43 |
| ▸ | PRKCB | P05771 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 1/20 | 0.43 |
| ▸ | PRKCH | P24723 | 1/20 | 0.43 |
| ▸ | AKT1 | P31749 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Glycerin SCHEMBL28048922 | 0.86 | LPAR1 (0.64) | LPAR3LPAR1LPAR2LPAR6LPAR4 | |
| SCHEMBL6225095 | 0.86 | LPAR3 (0.77) | LPAR3LPAR1LPAR2LPAR6LPAR4 | |
| SCHEMBL30443625 | 0.86 | LPAR3 (0.77) | LPAR3LPAR1LPAR2LPAR6LPAR4 | |
| SCHEMBL30556755 | 0.86 | LPAR3 (0.77) | LPAR3LPAR1LPAR2LPAR6LPAR4 | |
| SCHEMBL3261983 | 0.84 | LPAR3 (0.74) | LPAR3LPAR1LPAR2LPAR6LPAR4 | |
| SCHEMBL1534300 | 0.84 | LPAR3 (0.74) | LPAR3LPAR1LPAR2LPAR6LPAR4 | |
| SCHEMBL4435249 | 0.84 | LPAR3 (0.74) | LPAR3LPAR1LPAR2LPAR6LPAR4 | |
| SCHEMBL1333581 | 0.84 | LPAR1 (0.69) | LPAR3LPAR1LPAR2LPAR6LPAR4 | |
| Monoethanolamine SCHEMBL28048917 | 0.83 | LPAR1 (0.64) | LPAR3LPAR1LPAR2LPAR6LPAR4 | |
| Monoethanolamine SCHEMBL27910098 | 0.83 | LPAR1 (0.64) | LPAR3LPAR1LPAR2LPAR6LPAR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-62051690-A | — | — | None | — | — | JP | disclosed |
| JP-S6251690-A | PHOSPHORIC ACID ESTER | KAO CORP | 1987-03-06 | — | — | JP | disclosed |