Sugi Predict

Sugi Predict / Compounds / SCHEMBL1076263

SCHEMBL1076263

SCHEMBL1076263

CC1CCC(C(C)C)C(OC2CC(C)CCC2C(C)C)C1

nearest known ligand 0.56

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 4/20 0.56
▸ NFE2L2 Q16236 1/20 0.54
▸ TRPM8 Q7Z2W7 3/20 0.54
▸ TRPA1 O75762 2/20 0.54
▸ EPHX1 P07099 3/20 0.49
▸ LMNA P02545 2/20 0.47
▸ HPGD P15428 1/20 0.44
▸ CYP19A1 P11511 2/20 0.43
▸ CA1 P00915 1/20 0.43
▸ CA2 P00918 1/20 0.43
▸ KDM4E B2RXH2 1/20 0.43
▸ APOBEC3A P31941 1/20 0.43
▸ APOBEC3G Q9HC16 1/20 0.43
▸ GAA P10253 1/20 0.42
▸ MEN1 O00255 2/20 0.41
▸ KMT2A Q03164 2/20 0.41
▸ P2RX4 Q99571 1/20 0.40
▸ NTSR1 P30989 1/20 0.39
▸ NPSR1 Q6W5P4 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Formaldehyde SCHEMBL7793280 0.94 NFE2L2 (0.54) ALDH1A1NFE2L2TRPM8TRPA1EPHX1
SCHEMBL3675071 0.86 ALDH1A1 (0.56) ALDH1A1NFE2L2TRPM8TRPA1EPHX1
SCHEMBL3405364 0.86 EPHX1 (0.50) ALDH1A1NFE2L2TRPM8TRPA1EPHX1
Glycerin SCHEMBL722939 0.86 LMNA (0.50) ALDH1A1NFE2L2TRPM8TRPA1EPHX1
SCHEMBL13927583 0.84 ALDH1A1 (0.54) ALDH1A1NFE2L2TRPM8TRPA1EPHX1
SCHEMBL2609249 0.84 ALDH1A1 (0.54) ALDH1A1NFE2L2TRPM8TRPA1EPHX1
SCHEMBL3338174 0.84 ALDH1A1 (0.54) ALDH1A1NFE2L2TRPM8TRPA1EPHX1
SCHEMBL21610687 0.84 ALDH1A1 (0.54) ALDH1A1NFE2L2TRPM8TRPA1EPHX1
SCHEMBL14515031 0.84 ALDH1A1 (0.54) ALDH1A1NFE2L2TRPM8TRPA1EPHX1
SCHEMBL117885 0.84 ALDH1A1 (0.54) ALDH1A1NFE2L2TRPM8TRPA1EPHX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 530 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260047994-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL SYMRISE AG (DE) 2026-02-19 — — US claimed
US-20250325463-A1 COMPOSITIONS (III) SYMRISE AG (DE) 2025-10-23 — — US claimed
EP-4622621-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL Symrise AG (DE) 2025-10-01 — — EP claimed
EP-4472606-A1 COMPOSITIONS (III) Symrise AG (DE) 2024-12-11 — — EP claimed
US-20240358611-A1 COMPOSITIONS SYMRISE AG (DE) 2024-10-31 — — US claimed
EP-4429465-A1 COMPOSITIONS COMPRISING TRPM8 AGONISTIC COOLING AGENTS Symrise AG (DE) 2024-09-18 — — EP claimed
US-20240225915-A1 COMPOSITIONS FOR FIGHTING MALODORS SYMRISE AG (DE) 2024-07-11 — — US claimed
EP-4387587-A1 COMPOSITIONS Symrise AG (DE) 2024-06-26 — — EP claimed
WO-2024110515-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL SYMRISE AG (DE) 2024-05-30 — — WO claimed
EP-4351667-A1 COMPOSITIONS FOR FIGHTING MALODORS Symrise AG (DE) 2024-04-17 — — EP claimed
US-20100076080-A1 Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products THE PROCTER & GAMBLE COMPANY 2010-03-25 — — US claimed
WO-2010019730-A1 SYNTHESIS OF CYCLOHEXANE DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS THE PROCTER & GAMBLE COMPANY (US) 2010-02-18 — — WO claimed
US-20080317923-A1 AROMA COMPOSITION FOR REDUCING OR SUPPRESSING AN UNDESIRED BITTER, ASTRINGENT IMPRESSION SYMRISE GMBH & CO. KG (DE) 2008-12-25 — — US claimed
US-20080175800-A1 USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES SYMRISE GMBH & CO. KG (DE) 2008-07-24 — — US claimed
EP-0888067-B1 CHEWABLE COMPOSITIONS NIENABER PAUL DR (DE) 2003-12-03 — — EP claimed
US-6231900-B1 CANDY FOR TREATMENT OF COUGH AND COLD SYMPTOMS, COOLANTS AND FLAVORS THE PROCTER & GAMBLE COMPANY 2001-05-15 — — US claimed
EP-0888067-A4 CHEWABLE COMPOSITIONS PROCTER & GAMBLE (US) 2000-04-12 — — EP claimed
EP-0888067-A1 CHEWABLE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1999-01-07 — — EP claimed
WO-1997024036-A1 CHEWABLE COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1997-07-10 — — WO claimed
WO-1994008550-A1 ANAESTHETIC COMPOSITIONS THE PROCTER & GAMBLE COMPANY (US) 1994-04-28 — — WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240358611-A1 COMPOSITIONS AZI2, NISCH, CIP2A ALDH1A1 815/4885NFE2L2 1544/4885TRPM8 168/4885
US-20260047994-A1 AN ACTIVE COMPOSITION COMPRISING RETINOL RBP4, LRAT, RARB ALDH1A1 156/4885NFE2L2 3234/4885TRPM8 1615/4885
US-20100076080-A1 Synthesis of Cyclohexane Derivatives Useful as Sensates in Consumer Products NISCH, TRPM4, TRPM8 ALDH1A1 545/4885NFE2L2 2469/4885TRPM8 3/4885
US-20080175800-A1 USE OF SPECIFIC MENTHYL 3-OXOCARBOXYLIC ACID ESTERS AS PHYSIOLOGICALLY ACTIVE COOLING SUBSTANCES ECI1, OTC, MDH2 ALDH1A1 748/4885NFE2L2 2612/4885TRPM8 528/4885
US-20250325463-A1 COMPOSITIONS (III) NISCH, TAS1R3, TAS2R3 ALDH1A1 1377/4885NFE2L2 1069/4885TRPM8 171/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.