Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | ATM | Q13315 | 2/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 2/20 | 0.44 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | DRD4 | P21917 | 1/20 | 0.44 |
| ▸ | DRD3 | P35462 | 1/20 | 0.44 |
| ▸ | FAAH | O00519 | 1/20 | 0.43 |
| ▸ | MGLL | Q99685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10856538 | 0.87 | GAA (0.58) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL11206897 | 0.85 | ALDH1A1 (0.54) | MAPTTSHRKDM4EALDH1A1HTT | |
| SCHEMBL10860653 | 0.84 | SIGMAR1 (0.54) | SIGMAR1TSHRGAAHTTATM | |
| SCHEMBL11194501 | 0.81 | LMNA (0.51) | TSHRKDM4EALDH1A1GAAHTT | |
| SCHEMBL10851723 | 0.80 | TNKS (0.50) | TSHRKDM4EALDH1A1GAAHTT | |
| SCHEMBL16825908 | 0.80 | SIGMAR1 (0.57) | SIGMAR1MAPTTSHRKDM4EALDH1A1 | |
| SCHEMBL11196110 | 0.79 | ALDH1A1 (0.50) | MAPTTSHRALDH1A1GAAHTT | |
| SCHEMBL11197047 | 0.79 | KDM4E (0.52) | MAPTKDM4EGAAL3MBTL1DRD2 | |
| SCHEMBL11201299 | 0.76 | USP2 (0.50) | TSHRALDH1A1GAAATMFAAH | |
| SCHEMBL11197942 | 0.75 | HRH3 (0.45) | TSHRNPC1RAB9AGAAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |