Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 6/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 3/20 | 0.43 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | DRD4 | P21917 | 2/20 | 0.42 |
| ▸ | BCHE | P06276 | 2/20 | 0.42 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | DRD3 | P35462 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10914047 | 0.90 | HSD11B1 (0.50) | BCHEACHENR3C1ALDH1A1LMNA | |
| Hydrochloric Acid SCHEMBL10916739 | 0.89 | HSD11B1 (0.49) | BCHEACHENR3C1ALDH1A1LMNA | |
| SCHEMBL10922313 | 0.84 | MEN1 (0.51) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10917978 | 0.82 | ALDH1A1 (0.49) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10916248 | 0.81 | ALDH1A1 (0.51) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10914304 | 0.81 | ACHE (0.44) | KMT2ADRD4BCHEACHEALDH1A1 | |
| SCHEMBL10918979 | 0.80 | ALDH1A1 (0.52) | KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10967209 | 0.80 | POLB (0.50) | KMT2ADRD2CCR3DRD4DRD3 | |
| Hydrochloric Acid SCHEMBL10922643 | 0.79 | POLB (0.42) | KMT2ADRD2DRD3ALDH1A1LMNA | |
| SCHEMBL10920934 | 0.79 | TSHR (0.51) | KMT2AALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0064707-B1 | 4-(4-PHENYL-1-PIPERIDINYL)METHYL-5-ACYL-1,3-DIHYDRO-2H-IMIDAZOL-2-ONES | MERRELL DOW PHARMACEUTICALS INC. (US) | 1986-07-23 | — | — | EP | disclosed |
| EP-0064707-A1 | 4-(4-Phenyl-1-piperidinyl)methyl-5-acyl-1,3-dihydro-2H-imidazol-2-ones | MERRELL DOW PHARMACEUTICALS INC. (US) | 1982-11-17 | — | — | EP | disclosed |