Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAAA | Q02083 | 1/20 | 0.39 |
| ▸ | KDM1A | O60341 | 2/20 | 0.38 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.33 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | DRD1 | P21728 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | HTR2B | P41595 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1096281 | 0.84 | NAAA (0.36) | NAAAKDM1AKDM1BDGAT1ALDH1A1 | |
| SCHEMBL1021390 | 0.80 | DGAT1 (0.40) | NAAAKDM1AKDM1BDGAT1ALDH1A1 | |
| SCHEMBL188261 | 0.79 | ALOX15 (0.38) | ALDH1A1HPGDABCB11NR3C1CYP1A2 | |
| SCHEMBL29564714 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDABCB11NR3C1CYP1A2 | |
| SCHEMBL156589 | 0.79 | ALDH1A1 (0.38) | ALDH1A1HPGDABCB11NR3C1CYP1A2 | |
| SCHEMBL2719590 | 0.77 | KDM1A (0.36) | KDM1AKDM1BDGAT1ALDH1A1HPGD | |
| SCHEMBL348654 | 0.76 | ALDH1A1 (0.33) | ALDH1A1HPGDABCB11NR3C1CYP1A2 | |
| SCHEMBL990169 | 0.76 | ABCB11 (0.33) | ALDH1A1HPGDABCB11NR3C1CYP1A2 | |
| SCHEMBL1457482 | 0.76 | SIGMAR1 (0.44) | ALDH1A1HPGDABCB11NR3C1CYP1A2 | |
| SCHEMBL30298623 | 0.76 | HTR2B (0.33) | ALDH1A1HPGDABCB11NR3C1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 115 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3221309-B1 | NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS | COUNCIL SCIENT IND RES (IN) | 2019-11-13 | — | — | EP | claimed |
| EP-3253750-B1 | NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF | COUNCIL SCIENT IND RES (IN) | 2019-04-10 | — | — | EP | claimed |
| US-10221165-B2 | Flavone based EGFR inhibitors and process for preparation thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2019-03-05 | — | — | US | claimed |
| US-20180016268-A1 | Novel Flavone Based EGFR Inhibitors and Process for Preparation Thereof | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2018-01-18 | — | — | US | claimed |
| US-9862712-B2 | Benzimidazole based EGFR inhibitors | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-01-09 | — | — | US | claimed |
| EP-3221309-A1 | NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS | Council of Scientific and Industrial Research (IN) | 2017-09-27 | — | — | EP | claimed |
| US-20170267671-A1 | NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2017-09-21 | — | — | US | claimed |
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (WUXI) COMPANY, INC. (CN) | 2016-09-01 | — | — | US | claimed |
| WO-2016125186-A1 | NOVEL FLAVONE BASED EGFR INHIBITORS AND PROCESS FOR PREPARATION THEREOF | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-08-11 | — | — | WO | claimed |
| EP-3034076-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | JC (Wuxi) COMPANY, Inc. (CN) | 2016-06-22 | — | — | EP | claimed |
| WO-2016079763-A1 | NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-05-26 | — | — | WO | claimed |
| US-20250042883-A1 | GLP-1R AGONISTS AND USES THEREOF | QILU REGOR THERAPEUTICS INC. (CN) | 2025-02-06 | — | — | US | disclosed |
| EP-3446689-B1 | ISOTHIOCYANATE COMPOUND FOR USE IN THE TREATMENT OF HYPERBILIRUBINEMIA | JC WUXI COMPANY INC (CN) | 2025-01-08 | — | — | EP | disclosed |
| CN-118873522-A | Application of isothiocyanate compound | 无锡杰西医药股份有限公司 | 2024-11-01 | — | — | CN | disclosed |
| CN-113262218-B | Use of isothiocyanate compounds | 无锡杰西医药股份有限公司 | 2024-06-18 | — | — | CN | disclosed |
| WO-2004100881-A2 | PREPARATION AND USE OF ARYL ALKYL ACID DERIVATIVES FOR THE TREATMENT OF OBESITY | BAYER PHARMACEUTICALS CORPORATION (US) | 2004-11-25 | — | — | WO | disclosed |
| US-20040224997-A1 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | BAYER PHARMACEUTICALS CORPORATION | 2004-11-11 | — | — | US | disclosed |
| US-4380466-A | HERBICIDES | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1983-04-19 | — | — | US | disclosed |
| EP-0040849-A1 | Hexahydroisoindole derivatives, process for producing said compounds and herbicides containing said compounds | Takeda Chemical Industries, Ltd. (JP) | 1981-12-02 | — | — | EP | disclosed |
| US-4138242-A | Novel 2-aryl-2,3,5,6,7,8-hexahydro-3-thioxoimidazo-[1,5-a-]pyridin-1(BaH)-ones as herbicides | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1979-02-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160250175-A1 | COMBINED APPLICATION OF ISOTHIOCYANATE COMPOUND AND ANTI-CANCER MEDICINE | CHUK, KIT, MKI67 | NAAA 3936/4885KDM1A 1678/4885KDM1B 1304/4885 |
| US-20040224997-A1 | Preparation and use of aryl alkyl acid derivatives for the treatment of obesity | FABP4, GPR119, LIPC | NAAA 239/4885KDM1A 488/4885KDM1B 495/4885 |
| US-20170267671-A1 | NOVEL BENZIMIDAZOLE BASED EGFR INHIBITORS | EGFR, ERBB4, ERBB2 | NAAA 4488/4885KDM1A 2264/4885KDM1B 1743/4885 |
| US-20250042883-A1 | GLP-1R AGONISTS AND USES THEREOF | GLP1R, GPR119, GIPR | NAAA 3212/4885KDM1A 3629/4885KDM1B 3433/4885 |
| US-20180016268-A1 | Novel Flavone Based EGFR Inhibitors and Process for Preparation Thereof | EGFR, ERBB2, ABL1 | NAAA 3888/4885KDM1A 1944/4885KDM1B 2500/4885 |
| US-10221165-B2 | Flavone based EGFR inhibitors and process for preparation thereof | EGFR, ERBB2, ABL1 | NAAA 3983/4885KDM1A 1662/4885KDM1B 2143/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.