Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | PNMT | P11086 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 1/20 | 0.43 |
| ▸ | PTPRG | P23470 | 1/20 | 0.43 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | IDO1 | P14902 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11331947 | 0.87 | SIGMAR1 (0.51) | HTTTAAR1ALDH1A1 | |
| SCHEMBL8984622 | 0.79 | PNMT (0.54) | PNMTTAAR1PTPRCPTPRGIDO1 | |
| SCHEMBL10887037 | 0.78 | PTGS2 (0.69) | CYP3A4LMNATSHRKMT2A | |
| SCHEMBL6194277 | 0.78 | PNMT (0.58) | PNMTTAAR1PTPRCPTPRGIDO1 | |
| SCHEMBL2547244 | 0.76 | AKR1B1 (0.63) | PNMTTAAR1IDO1TSHRAKR1B1 | |
| SCHEMBL3086828 | 0.76 | PNMT (0.56) | PNMTTAAR1PTPRCPTPRGIDO1 | |
| SCHEMBL6961042 | 0.76 | PNMT (0.56) | PNMTTAAR1PTPRCPTPRGIDO1 | |
| SCHEMBL29965785 | 0.75 | NLRP3 (0.51) | HTTPNMTIDO1ALDH1A1LMNA | |
| SCHEMBL8754119 | 0.75 | LMNA (0.49) | PNMTTAAR1PTPRCPTPRGSLC6A4 | |
| SCHEMBL705708 | 0.75 | NLRP3 (0.51) | HTTPNMTIDO1ALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0044119-B1 | PROCESS FOR THE PREPARATION OF COPOLYMERS OF ETHYLENE WITH AT LEAST ONE OTHER 1-ALKENE | STAMICARBON B.V. (NL) | 1985-05-29 | — | — | EP | disclosed |
| US-4435552-A | COORDINATION CATALYST CONTAINING HALOACYL COMPOUND | STAMICARBON B.V. (NL) | 1984-03-06 | — | — | US | disclosed |
| EP-0044119-A2 | Process for the preparation of copolymers of ethylene with at least one other 1-alkene | STAMICARBON B.V. (NL) | 1982-01-20 | — | — | EP | disclosed |