SCHEMBL11044686

SCHEMBL11044686

CC(C)NCCCCNCCCNC(C)C

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 3/20 0.48
CYP1A2 P05177 3/20 0.48
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
TSHR P16473 2/20 0.43
ALDH1A1 P00352 1/20 0.43
GLA P06280 1/20 0.43
HRH4 Q9H3N8 2/20 0.38
HRH3 Q9Y5N1 2/20 0.38
CA12 O43570 3/20 0.38
CA2 P00918 3/20 0.38
CA4 P22748 3/20 0.38
CA6 P23280 3/20 0.38
CA5A P35218 3/20 0.38
CA7 P43166 3/20 0.38
CA9 Q16790 3/20 0.38
CA14 Q9ULX7 3/20 0.38
CA5B Q9Y2D0 3/20 0.38
CA3 P07451 2/20 0.38
F13A1 P00488 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12319688 1.00 CYP2C19 (0.48) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL25566471 0.97 TSHR (0.45) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL25565749 0.97 CYP2C19 (0.45) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL26107079 0.94 CYP2C19 (0.43) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL25566216 0.92 CYP2C19 (0.41) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL24013256 0.90 TSHR (0.62) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL18788095 0.90 TSHR (0.48) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL12323375 0.90 CYP2C19 (0.40) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL20738397 0.90 CYP2C19 (0.40) CYP2C19CYP1A2MEN1KMT2ATSHR
SCHEMBL23739843 0.90 CYP2C19 (0.40) CYP2C19CYP1A2MEN1KMT2ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY TIBA BIOTECH LLC (US) 2023-05-18 US disclosed
US-11584933-B2 RNA interference in ocular indications PHIO PHARMACEUTICALS CORP. (US) 2023-02-21 US disclosed
US-20230002766-A1 CHEMICALLY MODIFIED OLIGONUCLEOTIDES TARGETING BROMODOMAIN CONTAINING PROTEIN 4 (BRD4) FOR IMMUNOTHERAPY PHIO PHARMACEUTICALS CORP. (US) 2023-01-05 US disclosed
US-20210348169-A1 METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 PHIO PHARMACEUTICALS CORP. (US) 2021-11-11 US disclosed
US-11021707-B2 Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA PHIO PHARMACEUTICALS CORP. (US) 2021-06-01 US disclosed
US-11001845-B2 Nucleic acid molecules targeting superoxide dismutase 1 (SOD1) PHIO PHARMACEUTICALS CORP. (US) 2021-05-11 US disclosed
US-20210062195-A1 RNA INTERFERENCE IN OCULAR INDICATIONS PHIO PHARMACEUTICALS CORP. (US) 2021-03-04 US disclosed
US-10913948-B2 RNA interference in dermal and fibrotic indications PHIO PHARMACEUTICALS CORP. (US) 2021-02-09 US disclosed
US-10808247-B2 Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach PHIO PHARMACEUTICALS CORP. (US) 2020-10-20 US disclosed
US-10662430-B2 RNA interference in ocular indications PHIO PHARMACEUTICALS CORP. (US) 2020-05-26 US disclosed
US-20190048341-A1 REDUCED SIZE SELF-DELIVERING NUCLEIC ACID COMPOUNDS TARGETING LONG NON-CODING RNA RXI PHARMACEUTICALS CORPORATION (US) 2019-02-14 US disclosed
US-10184124-B2 RNA interference in ocular indications PHIO PHARMACEUTICALS CORP. (US) 2019-01-22 US disclosed
US-20180195072-A1 NUCLEIC ACID MOLECULES TARGETING SUPEROXIDE DISMUTASE 1 (SOD1) RXI PHARMACEUTICALS CORPORATION (US) 2018-07-12 US disclosed
US-20180195066-A1 METHODS FOR TREATING NEUROLOGICAL DISORDERS USING A SYNERGISTIC SMALL MOLECULE AND NUCLEIC ACIDS THERAPEUTIC APPROACH RXI PHARMACEUTICALS CORPORATION (US) 2018-07-12 US disclosed
US-9963702-B2 RNA interference in dermal and fibrotic indications RXI PHARMACEUTICALS CORPORATION (US) 2018-05-08 US disclosed
US-20180030451-A1 METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 RXI PHARMACEUTICALS CORPORATION (US) 2018-02-01 US disclosed
US-20170067056-A1 RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS RXI PHARMACEUTICALS CORPORATION (US) 2017-03-09 US disclosed
US-20170051290-A1 METHODS FOR TREATMENT OF DISORDERS IN THE FRONT OF THE EYE UTILIZING NUCLEIC ACID MOLECULES RXI PHARMACEUTICALS CORPORATION (US) 2017-02-23 US disclosed
WO-2011119887-A1 RNA INTERFERENCE IN DERMAL AND FIBROTIC INDICATIONS RXI PHARMACEUTICALS CORPORATION (US) 2011-09-29 WO disclosed
US-4442305-A FOR USE IN CITRO OR IN VIVO THE UNITED STATES OF AMERICA AS REPRESENTED BY THE UNITED STATES DEPARTMENT OF ENERGY (US) 1984-04-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180195066-A1 METHODS FOR TREATING NEUROLOGICAL DISORDERS USING A SYNERGISTIC SMALL MOLECULE AND NUCLEIC ACIDS THERAPEUTIC APPROACH SOD1, POLRMT, SMN1; SMN2 CYP2C19 4885/4885CYP1A2 4860/4885MEN1 4147/4885
US-11021707-B2 Reduced size self-delivering nucleic acid compounds targeting long non-coding RNA SNRPA, SNRPE, NSUN3 CYP2C19 4882/4885CYP1A2 4878/4885MEN1 1987/4885
US-11584933-B2 RNA interference in ocular indications RXRA, RXRB, RXRG CYP2C19 4442/4885CYP1A2 4032/4885MEN1 4837/4885
US-10808247-B2 Methods for treating neurological disorders using a synergistic small molecule and nucleic acids therapeutic approach SOD1, POLRMT, SMN1; SMN2 CYP2C19 4885/4885CYP1A2 4860/4885MEN1 4147/4885
US-20230002766-A1 CHEMICALLY MODIFIED OLIGONUCLEOTIDES TARGETING BROMODOMAIN CONTAINING PROTEIN 4 (BRD4) FOR IMMUNOTHERAPY BRD4, BRDT, BRPF3 CYP2C19 4885/4885CYP1A2 4883/4885MEN1 3905/4885
US-11001845-B2 Nucleic acid molecules targeting superoxide dismutase 1 (SOD1) SOD1, SOD3, POLRMT CYP2C19 4876/4885CYP1A2 4809/4885MEN1 4540/4885
US-20170051290-A1 METHODS FOR TREATMENT OF DISORDERS IN THE FRONT OF THE EYE UTILIZING NUCLEIC ACID MOLECULES POLRMT, NSUN3, ELAVL1 CYP2C19 4881/4885CYP1A2 4865/4885MEN1 1278/4885
US-20180030451-A1 METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 MMP1, MMP3, MMP11 CYP2C19 4841/4885CYP1A2 4667/4885MEN1 4561/4885
US-20230149562-A1 CARRIERS FOR EFFICIENT NUCLEIC ACID DELIVERY POLN, TLR9, TSG101 CYP2C19 4867/4885CYP1A2 4870/4885MEN1 2899/4885
US-20210062195-A1 RNA INTERFERENCE IN OCULAR INDICATIONS RXRA, RXRB, RXRG CYP2C19 4442/4885CYP1A2 4032/4885MEN1 4837/4885
US-10184124-B2 RNA interference in ocular indications RXRA, RXRB, RXRG CYP2C19 4442/4885CYP1A2 4032/4885MEN1 4837/4885
US-20210348169-A1 METHODS FOR TREATING AGING AND SKIN DISORDERS USING NUCLEIC ACIDS TARGETING TYR OR MMP1 MMP1, MMP3, MMP11 CYP2C19 4841/4885CYP1A2 4667/4885MEN1 4561/4885
US-10662430-B2 RNA interference in ocular indications RXRA, RXRB, RXRG CYP2C19 4442/4885CYP1A2 4032/4885MEN1 4837/4885
US-20180195072-A1 NUCLEIC ACID MOLECULES TARGETING SUPEROXIDE DISMUTASE 1 (SOD1) SOD1, SOD3, POLRMT CYP2C19 4876/4885CYP1A2 4809/4885MEN1 4540/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.