Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.43 |
| ▸ | HTR3B | O95264 | 1/20 | 0.43 |
| ▸ | HTR3A | P46098 | 1/20 | 0.43 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.43 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | PNP | P00491 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16825664 | 0.79 | ALDH1A1 (0.45) | ALDH1A1HTTSMN1; SMN2HTR3EHTR3B | |
| SCHEMBL10856538 | 0.78 | GAA (0.58) | ALDH1A1HTTTSHRMAPTMEN1 | |
| SCHEMBL11194501 | 0.75 | LMNA (0.51) | ALDH1A1HTTTSHRMEN1KMT2A | |
| SCHEMBL10851723 | 0.74 | TNKS (0.50) | ALDH1A1HTTCYP2D6CYP2C9CYP2C19 | |
| SCHEMBL11196310 | 0.74 | KMT2A (0.52) | ALDH1A1HTTMEN1KMT2AKDM4E | |
| SCHEMBL6695193 | 0.73 | ALDH1A1 (0.53) | ALDH1A1HTTSMN1; SMN2CYP2D6CYP2C9 | |
| SCHEMBL11197047 | 0.73 | KDM4E (0.52) | HTR3EHTR3BHTR3AHTR3DHTR3C | |
| SCHEMBL11196110 | 0.73 | ALDH1A1 (0.50) | ALDH1A1HTTTSHRMAPTMEN1 | |
| SCHEMBL11206897 | 0.72 | ALDH1A1 (0.54) | ALDH1A1HTTTSHRMAPTMEN1 | |
| SCHEMBL11200656 | 0.72 | SIGMAR1 (0.57) | ALDH1A1HTTTSHRMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4421753-A | HYPOTENSIVE AGENTS | AMERICAN CYANAMID COMPANY (US) | 1983-12-20 | — | — | US | claimed |