SCHEMBL1126539

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127168	0.84	CHRNA7 (0.39)	TRPV1MOKCHRNA7KCNH2SMN1; SMN2
	SCHEMBL1126696	0.76	MAPT (0.50)	SMN1; SMN2KDM4EMEN1NPC1ALDH1A1
	SCHEMBL1127228	0.76	FAAH (0.40)	SMN1; SMN2NPC1ALDH1A1HTTMAPT
	SCHEMBL1127110	0.75	L3MBTL1 (0.46)	TRPV1KCNH2MCHR1KDM4EMAPT
	SCHEMBL1127109	0.73	MAPT (0.52)	SMN1; SMN2MEN1NPC1ALDH1A1KMT2A
	SCHEMBL1126649	0.72	ALDH1A1 (0.43)	MOKSMN1; SMN2NPC1ALDH1A1HSD17B10
	SCHEMBL1126487	0.72	MAPT (0.51)	CHRNA7SMN1; SMN2MEN1NPC1ALDH1A1
	SCHEMBL1126812	0.71	ALDH1A1 (0.48)	SMN1; SMN2KDM4EMEN1NPC1ALDH1A1
	SCHEMBL19661313	0.71	GAA (0.42)	MEN1NPC1ALDH1A1KMT2AHSD17B10
	SCHEMBL1127172	0.70	NPY2R (0.45)	SMN1; SMN2KDM4EMEN1NPC1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.