SCHEMBL1126812

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1126931	0.81	RAB9A (0.46)	ALDH1A1SMN1; SMN2POLBPKMKMT2A
	SCHEMBL1127228	0.81	FAAH (0.40)	ALDH1A1SMN1; SMN2POLBLMNAHTT
	SCHEMBL1127545	0.79	RAB9A (0.50)	ALDH1A1SMN1; SMN2POLBPKMLMNA
	SCHEMBL1126696	0.79	MAPT (0.50)	ALDH1A1SMN1; SMN2POLBMAPK1PKM
	SCHEMBL1126720	0.79	TNF (0.44)	ALDH1A1SMN1; SMN2MAPK1KMT2ALMNA
	SCHEMBL1126487	0.78	MAPT (0.51)	ALDH1A1SMN1; SMN2POLBMAPK1PKM
	SCHEMBL1992485	0.78	ALDH1A1 (0.48)	ALDH1A1MAPK1KMT2ALMNAHTT
	SCHEMBL30235329	0.78	ALDH1A1 (0.48)	ALDH1A1MAPK1KMT2ALMNAHTT
	SCHEMBL1644498	0.78	L3MBTL1 (0.62)	ALDH1A1SMN1; SMN2POLBSTAT3TAAR1
	SCHEMBL1993111	0.77	ALDH1A1 (0.42)	ALDH1A1SMN1; SMN2POLBMAPK1JAK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.