Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRNA7 | P36544 | 5/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.39 |
| ▸ | MCHR1 | Q99705 | 2/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.37 |
| ▸ | HTR3A | P46098 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1126539 | 0.84 | TRPV1 (0.40) | CHRNA7KCNH2MCHR1HTR2CMOK | |
| SCHEMBL1127158 | 0.76 | FAAH (0.42) | KDM4EMEN1NPC1ALDH1A1HPGD | |
| SCHEMBL1127139 | 0.72 | MAPT (0.48) | MEN1NPC1ALDH1A1KMT2AHSD17B10 | |
| SCHEMBL1126595 | 0.68 | RAB9A (0.48) | KDM4EMEN1NPC1KMT2AHSD17B10 | |
| SCHEMBL1126561 | 0.66 | MAPT (0.41) | KDM4EMEN1NPC1ALDH1A1KMT2A | |
| SCHEMBL1126843 | 0.66 | SLC1A2 (0.41) | HTR2CMEN1NPC1KMT2AHTT | |
| SCHEMBL1126845 | 0.66 | HCRTR1 (0.41) | CHRNA7MEN1NPC1ALDH1A1KMT2A | |
| SCHEMBL1126575 | 0.63 | MCHR1 (0.36) | MCHR1KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL1127407 | 0.63 | PTGS2 (0.49) | KCNH2KDM4EMEN1NPC1ALDH1A1 | |
| SCHEMBL1126693 | 0.62 | MEN1 (0.49) | KDM4EMEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |