SCHEMBL1126635

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1127228	0.88	FAAH (0.40)	JAK3NTRK1SMN1; SMN2MAPTNPC1
	SCHEMBL1988597	0.83	IL2 (0.41)	NTRK1SMN1; SMN2MAPTLMNAALDH1A1
	SCHEMBL1127172	0.76	NPY2R (0.45)	SMN1; SMN2MAPTNPC1RAB9APOLB
	SCHEMBL1126812	0.75	ALDH1A1 (0.48)	SMN1; SMN2NPC1RAB9APOLBLMNA
	SCHEMBL30234815	0.75	ALDH1A1 (0.43)	SMN1; SMN2MAPTNPC1RAB9ALMNA
	SCHEMBL1127213	0.75	NPC1 (0.39)	SMN1; SMN2MAPTNPC1RAB9AALDH1A1
	SCHEMBL1990361	0.75	ALDH1A1 (0.43)	SMN1; SMN2MAPTNPC1RAB9ALMNA
	SCHEMBL1126931	0.74	RAB9A (0.46)	SMN1; SMN2MAPTNPC1RAB9APOLB
	SCHEMBL1127110	0.71	L3MBTL1 (0.46)	MAPTRAB9A
	SCHEMBL1644368	0.71	SMN1; SMN2 (0.51)	JAK3NTRK1SMN1; SMN2MAPTNPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.