Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | MMP9 | P14780 | 7/20 | 0.38 |
| ▸ | MMP2 | P08253 | 6/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.38 |
| ▸ | MMP13 | P45452 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.34 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.34 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2887982 | 0.85 | LMNA (0.64) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL4889487 | 0.77 | LMNA (0.73) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL11721680 | 0.76 | ALDH1A1 (0.48) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL11308156 | 0.76 | MMP9 (0.39) | LMNAMMP9TP53 | |
| SCHEMBL1683293 | 0.73 | LMNA (0.58) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL468545 | 0.69 | MMP9 (0.67) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL5450754 | 0.69 | MMP9 (0.67) | LMNAMMP9MMP2MMP8MMP13 | |
| Barbital SCHEMBL7348703 | 0.68 | LMNA (0.90) | LMNAMMP9MMP2MMP8MMP13 | |
| SCHEMBL12014051 | 0.68 | LMNA (0.50) | LMNAMMP9MMP2MMP8MMP13 | |
| Barbital SCHEMBL43818 | 0.67 | LMNA (1.00) | LMNAMMP9MMP2MMP8MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4344956-A | Oxotetrahydrothiophenes | ERCOLI NICOLO | 1982-08-17 | — | — | US | disclosed |