Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CDC7 | O00311 | 1/20 | 0.36 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.35 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | AXL | P30530 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 2/20 | 0.32 |
| ▸ | HTR1D | P28221 | 1/20 | 0.31 |
| ▸ | HTR1B | P28222 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1127138 | 0.68 | PYGL (0.34) | MEN1KMT2AMAPTHSD17B10CYP1A2 | |
| SCHEMBL1127404 | 0.67 | HSD17B10 (0.41) | MEN1KMT2AUSP2MAPTALOX15 | |
| SCHEMBL1127700 | 0.66 | KDM4E (0.40) | MEN1KMT2AMAPTHSD17B10KDM4E | |
| SCHEMBL3961016 | 0.65 | CES2 (0.59) | MEN1KMT2AUSP2MAPTALOX15 | |
| SCHEMBL26112712 | 0.65 | ALDH1A1 (0.48) | MEN1KMT2AMAPTALOX15HSD17B10 | |
| SCHEMBL11075494 | 0.62 | ALDH1A1 (0.38) | MEN1KMT2AMAPTHSD17B10 | |
| SCHEMBL1127001 | 0.62 | ADORA3 (0.39) | MEN1KMT2AUSP2MAPTALOX15 | |
| SCHEMBL1989501 | 0.60 | HSD17B10 (0.56) | MEN1KMT2AUSP2MAPTALOX15 | |
| SCHEMBL1126701 | 0.60 | MEN1 (0.36) | MEN1KMT2AUSP2MAPTALOX15 | |
| SCHEMBL31189473 | 0.59 | LMNA (0.39) | MEN1KMT2AMAPTALOX15HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2283006-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G Limited (GB) | 2011-02-16 | — | — | EP | disclosed |
| WO-2009130481-A1 | PYRROLE ANTIFUNGAL AGENTS | F2G LTD (GB) | 2009-10-29 | — | — | WO | disclosed |