Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 10/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29143247 | 0.85 | SIRT1 (0.47) | ALDH1A1GLAL3MBTL1CYP2C9HPGD | |
| SCHEMBL11427398 | 0.84 | ALDH1A1 (0.46) | SLC6A9ALDH1A1GLAL3MBTL1AGBL2 | |
| Oxirane SCHEMBL11442758 | 0.78 | SIRT1 (0.41) | ALDH1A1GLAL3MBTL1CYP2C9HPGD | |
| SCHEMBL11552435 | 0.75 | SLC6A2 (0.44) | ALDH1A1CYP2C9HPGDCYP2C19SIRT1 | |
| SCHEMBL26676266 | 0.75 | SIRT1 (0.51) | SLC6A9EPHX1ALDH1A1GLAL3MBTL1 | |
| SCHEMBL11430852 | 0.72 | MMP2 (0.60) | SLC6A9ALDH1A1PPARGPPARA | |
| SCHEMBL26068033 | 0.71 | SLC6A9 (0.48) | SLC6A9EPHX1ALDH1A1GLAL3MBTL1 | |
| SCHEMBL11442734 | 0.71 | AKR1B1 (0.53) | SLC6A9EPHX1AGBL2CYP2C9HPGD | |
| SCHEMBL4337657 | 0.71 | SLC6A9 (0.43) | SLC6A9EPHX1ALDH1A1GLAL3MBTL1 | |
| SCHEMBL11554666 | 0.70 | MMP2 (0.49) | ALDH1A1CYP2C9HPGDCYP2C19PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4228284-A | ANTIINFLAMMATORY AGENTS | Nippon Chemiphar Company, Limited (JP) | 1980-10-14 | — | — | US | disclosed |
| US-4166127-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1979-08-28 | — | — | US | disclosed |
| US-4101667-A | ANTIINFLAMMATORY AGENTS | NIPPON CHEMIPHAR CO., LTD. (JP) | 1978-07-18 | — | — | US | disclosed |