Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 5/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.53 |
| ▸ | THRB | P10828 | 1/20 | 0.53 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hexane SCHEMBL10697149 | 0.97 | ALDH1A1 (0.57) | TSHRALDH1A1THRBDNM1LMNA | |
| Hexane SCHEMBL95579 | 0.97 | ALDH1A1 (0.57) | TSHRALDH1A1THRBDNM1LMNA | |
| Hexane SCHEMBL10428089 | 0.93 | ALDH1A1 (0.53) | TSHRALDH1A1THRBDNM1LMNA | |
| Heptane SCHEMBL8040709 | 0.91 | TSHR (0.48) | TSHRALDH1A1THRBDNM1LMNA | |
| Pentane SCHEMBL1230691 | 0.90 | ALDH1A1 (0.57) | TSHRALDH1A1THRBLMNATDP1 | |
| Hexane SCHEMBL27545868 | 0.88 | ALDH1A1 (0.47) | TSHRALDH1A1THRBLMNAMEN1 | |
| Hexane SCHEMBL9152574 | 0.88 | ALDH1A1 (0.47) | TSHRALDH1A1THRBDNM1LMNA | |
| SCHEMBL28565424 | 0.87 | HTT (0.54) | TSHRALDH1A1THRBMEN1KMT2A | |
| Heptane SCHEMBL14119566 | 0.87 | SPHK1 (0.41) | TSHRALDH1A1THRBLMNAMEN1 | |
| Octanol SCHEMBL28830788 | 0.87 | ALDH1A1 (0.65) | TSHRALDH1A1THRBDNM1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 396 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0968197-B1 | EFFICIENT SYNTHESIS OF A 1,4-DIHYDRO-2H-3,1-BENZOXAZIN-2-ONE | MERCK & CO INC (US) | 2005-04-27 | — | — | EP | claimed |
| US-11964990-B2 | 1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[2,3-b][1,4]oxazepine bcl-2 inhibitors | ABBVIE INC. (US) | 2024-04-23 | — | — | US | disclosed |
| US-20240117249-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-04-11 | — | — | US | disclosed |
| CN-112279808-B | Cystic fibrosis transmembrane conductance regulator modulators | 弗特克斯药品有限公司 | 2024-03-08 | — | — | CN | disclosed |
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | MERCK PATENT GMBH (DE) | 2024-02-29 | — | — | US | disclosed |
| CN-112250627-B | Cystic fibrosis transmembrane conductance regulator modulators | 弗特克斯药品有限公司 | 2024-02-02 | — | — | CN | disclosed |
| US-20230322645-A1 | PROCESS FOR MAKING A CONJUGATED DIENE FROM AN ALLYL ALCOHOL | GIVAUDAN SA (CH) | 2023-10-12 | — | — | US | disclosed |
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | CAPSTAN THERAPEUTICS, INC. (US) | 2023-10-12 | — | — | US | disclosed |
| CN-116655618-A | Probes for imaging huntingtin | CHDI基金会股份有限公司 | 2023-08-29 | — | — | CN | disclosed |
| CN-116601265-A | Aromatic isothiocyanates | 默克专利股份有限公司 | 2023-08-15 | — | — | CN | disclosed |
| EP-0817764-A1 | PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1998-01-14 | — | — | EP | disclosed |
| WO-1997048401-A1 | DEOXY AND OXYGEN-SUBSTITUTED SUGAR-CONTAINING 14-AMINOSTEROID COMPOUNDS FOR USE AS AN ANTIARRHYTHMIC | THE PROCTER & GAMBLE COMPANY (US) | 1997-12-24 | — | — | WO | disclosed |
| CN-1135757-A | Novel deoxy and oxygen-substituted sugar-containing 14-aminosteroid compounds | PROCTER & GAMBLE (US) | 1996-11-13 | — | — | CN | disclosed |
| WO-1996030320-A1 | PREPARATION OF CIS-4-O-PROTECTED-2-CYCLOPENTENOL DERIVATIVES | HOECHST MARION ROUSSEL, INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| EP-0720616-A1 | NOVEL DEOXY AND OXYGEN-SUBSTITUTED SUGAR-CONTAINING 14-AMINOSTEROID COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1996-07-10 | — | — | EP | disclosed |
| WO-1995008558-A1 | NOVEL DEOXY AND OXYGEN-SUBSTITUTED SUGAR-CONTAINING 14-AMINOSTEROID COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1995-03-30 | — | — | WO | disclosed |
| US-5395845-A | Insecticides | ROUSSEL-UCLAF (FR) | 1995-03-07 | — | — | US | disclosed |
| CN-1081675-A | By the new pyrethroid of thiazolic alcohol derivative, its preparation method and as the purposes of agricultural chemicals | ROUSSEL UCLAF (FR) | 1994-02-09 | — | — | CN | disclosed |
| EP-0556123-A1 | Pyrethrinoid esters of thiazolylalcohols, process for their preparation and their use as pesticides | ROUSSEL UCLAF (FR) | 1993-08-18 | — | — | EP | disclosed |
| US-4988734-A | Fungicides | BAYER AKTIENGESELLSCHAFT (DE) | 1991-01-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240072425-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, TRPC1, CRY1 | TSHR 3948/4885ALDH1A1 1864/4885THRB 4307/4885 |
| US-20230320995-A1 | IONIZABLE CATIONIC LIPIDS AND LIPID NANOPARTICLES | PLTP, LNPEP, PLIN3 | TSHR 894/4885ALDH1A1 4315/4885THRB 1952/4885 |
| US-20230322645-A1 | PROCESS FOR MAKING A CONJUGATED DIENE FROM AN ALLYL ALCOHOL | ADH1C, ADH1A, ADH5 | TSHR 2518/4885ALDH1A1 17/4885THRB 2811/4885 |
| US-20240117249-A1 | AROMATIC ISOTHIOCYANATES | TRPA1, FOXM1, MAFG | TSHR 3456/4885ALDH1A1 2000/4885THRB 4009/4885 |
| US-11964990-B2 | 1,3,4,7-tetrahydro-2H-pyrrolo[3′,2′:5,6]pyrido[2,3-b][1,4]oxazepine bcl-2 inhibitors | BCL9L, BCL2L1, BCL9 | TSHR 2721/4885ALDH1A1 920/4885THRB 3052/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.