Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.43 |
| ▸ | RELA | Q04206 | 1/20 | 0.43 |
| ▸ | GSTO1 | P78417 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.41 |
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA4 | P22748 | 1/20 | 0.41 |
| ▸ | CA5A | P35218 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11558331 | 0.86 | MMP2 (0.53) | RAB9ANPC1MAPTHTTLMNA | |
| SCHEMBL11553624 | 0.81 | CYP2C19 (0.53) | MAPTHTTLMNAGSTO1BCAT1 | |
| SCHEMBL11554551 | 0.78 | CYP2C19 (0.57) | MAPTLMNAKMT2ABCAT1POLB | |
| SCHEMBL11559300 | 0.77 | RORC (0.43) | NPC1MAPTLMNANFKB1GSTO1 | |
| SCHEMBL11554465 | 0.75 | MAOB (0.46) | RAB9ANPC1MAPTHTTLMNA | |
| SCHEMBL11554345 | 0.74 | POLB (0.47) | RAB9ANPC1MAPTHTTLMNA | |
| SCHEMBL11554622 | 0.74 | GSTO1 (0.41) | MAPTHTTLMNAGSTO1KMT2A | |
| SCHEMBL11554724 | 0.73 | PRNP (0.45) | RAB9ANPC1MAPTHTTGSTO1 | |
| SCHEMBL11557173 | 0.72 | GSTO1 (0.55) | MAPTHTTGSTO1KMT2ASMN1; SMN2 | |
| SCHEMBL11026357 | 0.72 | POLB (0.65) | MAPTHTTGSTO1KMT2ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4156732-A | Certain pharmaceutical sulfamoylbenzoyl benzofurans, benzothiophenes, and indoles | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-05-29 | — | — | US | disclosed |
| EP-0000128-A1 | Sulfamoylaryl ketones, process for their preparation and their use as medicaments | HOECHST AKTIENGESELLSCHAFT (DE) | 1979-01-10 | — | — | EP | disclosed |