Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.36 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | GLA | P06280 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PPIB | P23284 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | MTOR | P42345 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557429 | 0.85 | MMP12 (0.38) | GAAALDH1A1KDM4EPOLBMAPT | |
| SCHEMBL11558220 | 0.84 | KCNE1 (0.34) | HIF1APGR | |
| SCHEMBL11558080 | 0.84 | MAPT (0.36) | GAAALDH1A1KDM4EMAPTKMT2A | |
| SCHEMBL11560192 | 0.84 | LMNA (0.38) | PGRNPSR1SMN1; SMN2 | |
| SCHEMBL11558077 | 0.84 | ATAD2 (0.38) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL11560034 | 0.81 | SMN1; SMN2 (0.37) | GAAALDH1A1KDM4EPOLBHPGD | |
| SCHEMBL11559426 | 0.81 | TRPV1 (0.35) | KCNH2MEN1KMT2A | |
| SCHEMBL11565708 | 0.81 | PTGS2 (0.34) | KCNH2L3MBTL1 | |
| SCHEMBL11560946 | 0.81 | ALPL (0.34) | GAAALDH1A1KDM4EPOLBNPSR1 | |
| SCHEMBL11560739 | 0.78 | NQO2 (0.40) | ALDH1A1KDM4EPOLBNPSR1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |