Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALPL | P05186 | 3/20 | 0.34 |
| ▸ | BRD4 | O60885 | 3/20 | 0.34 |
| ▸ | CREBBP | Q92793 | 3/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | GAA | P10253 | 3/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CNR2 | P34972 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11557429 | 0.84 | MMP12 (0.38) | BRD4CREBBPLMNAMAPTALDH1A1 | |
| SCHEMBL11560192 | 0.83 | LMNA (0.38) | LMNAPARP1SMN1; SMN2NPSR1 | |
| SCHEMBL11558077 | 0.83 | ATAD2 (0.38) | ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL11558220 | 0.83 | KCNE1 (0.34) | — | |
| SCHEMBL11558080 | 0.83 | MAPT (0.36) | BRD4CREBBPLMNAMAPTALDH1A1 | |
| SCHEMBL11559426 | 0.80 | TRPV1 (0.35) | MEN1KMT2ACYP2C9CYP2C19 | |
| SCHEMBL11560034 | 0.80 | SMN1; SMN2 (0.37) | LMNAALDH1A1GAASMN1; SMN2TDP1 | |
| SCHEMBL11565708 | 0.80 | PTGS2 (0.34) | BRD4CREBBP | |
| SCHEMBL11556858 | 0.77 | BRD4 (0.38) | BRD4CREBBP | |
| SCHEMBL11560739 | 0.77 | NQO2 (0.40) | BRD4CREBBPMAPTALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4134974-A | Imidazo[5,1-c][1,4]benzoxazin-1-one | CARLO ERBA S. P. A. (IT) | 1979-01-16 | — | — | US | disclosed |