SCHEMBL1158665

SCHEMBL1158665

C=CCB(CC=C)c1ccc(OCCCC)cc1CC=C

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 2/20 0.41
CNR1 P21554 1/20 0.39
CA12 O43570 1/20 0.37
CA1 P00915 1/20 0.37
CA2 P00918 1/20 0.37
CA3 P07451 1/20 0.37
CA4 P22748 1/20 0.37
CA6 P23280 1/20 0.37
CA7 P43166 1/20 0.37
CA9 Q16790 1/20 0.37
CA14 Q9ULX7 1/20 0.37
CA5B Q9Y2D0 1/20 0.37
NR5A1 Q13285 1/20 0.36
TSHR P16473 1/20 0.36
MAPT P10636 1/20 0.36
TDP1 Q9NUW8 1/20 0.36
LTA4H P09960 4/20 0.36
L3MBTL1 Q9Y468 1/20 0.35
GPBAR1 Q8TDU6 1/20 0.35
CYSLTR2 Q9NS75 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1159051 0.97 NR5A1 (0.41) CNR2CNR1NR5A1TSHRMAPT
SCHEMBL7168148 0.89 KDM4E (0.39) CNR2CA12CA1CA4CA6
SCHEMBL1159122 0.84 CNR2 (0.41) CNR2CNR1CA12CA1CA2
SCHEMBL7164350 0.82 ALDH1A1 (0.46) CNR2TSHRMAPTTDP1L3MBTL1
SCHEMBL1159239 0.82 NR5A1 (0.40) CNR2CNR1NR5A1TSHRMAPT
SCHEMBL7178229 0.80 NR5A1 (0.43) CNR2CNR1NR5A1TSHRMAPT
SCHEMBL1158940 0.79 THRB (0.37) CNR2CNR1CA1CA2MAPT
SCHEMBL8416721 0.77 CNR2 (0.53) CNR2CNR1NR5A1MAPTLTA4H
SCHEMBL11032751 0.77 CNR2 (0.61) CNR2CNR1NR5A1MAPTTDP1
SCHEMBL7165637 0.75 GABRA1 (0.35) CNR2CNR1TSHRMAPTGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 107 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME KURARAY NORITAKE DENTAL INC. (JP) 2024-05-23 US disclosed
US-11866590-B2 Diisocyanate-based radical polymerizable silane coupling compound having an urethane bond KABUSHIKI KAISHA SHOFU (JP) 2024-01-09 US disclosed
US-20230381066-A1 DENTAL CURABLE COMPOSITION HAVING GOOD COLOR COMPATIBILITY KURARAY NORITAKE DENTAL INC. (JP) 2023-11-30 US disclosed
EP-2979679-B1 CURABLE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2023-11-29 EP disclosed
EP-4268791-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME Kuraray Noritake Dental Inc. (JP) 2023-11-01 EP disclosed
EP-2216349-B1 USE OF A PHENOL TYPE COMPOUND IN A DENTAL CHEMICAL POLYMERIZATION CATALYST WITH IMPROVED POLYMERIZING ACTIVITY TOKUYAMA DENTAL CORP (JP) 2023-09-20 EP disclosed
EP-4238546-A1 DENTAL CURABLE COMPOSITION HAVING GOOD COLOR COMPATIBILITY Kuraray Noritake Dental Inc. (JP) 2023-09-06 EP disclosed
US-11607370-B2 Dental composition KURARAY NORITAKE DENTAL INC. (JP) 2023-03-21 US disclosed
EP-3782598-B1 ADHESIVE COMPOSITION FOR DENTAL USE KURARAY NORITAKE DENTAL INC (JP) 2023-02-15 EP disclosed
US-20230040426-A1 DENTAL RESTORATION MATERIAL COMPOSITION KURARAY NORITAKE DENTAL INC. (JP) 2023-02-09 US disclosed
US-6759449-B2 NONCROSSLINKING POLYMETHYL METHACRYLATE AND POLYETHYL METH-ACRYLATE SPHERICAL FILLER, UNSATURATED ACID FUNCTIONALIZED MONOMER AND POLYMERIZATION INITIATOR TOKUYAMA DENTAL CORPORATION (JP) 2004-07-06 US disclosed
US-20040006154-A1 Deantal catalyst for chemical polymerization and use thereof IBARAGI KAZUYA (JP) 2004-01-08 US disclosed
US-6660784-B2 Adhesives; mixture of peroxy compounds and tetraphenylborate as catalyst TOKUYAMA CORPORATION (JP) 2003-12-09 US disclosed
EP-0811368-B1 DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST TOKUYAMA CORP (JP) 2003-07-23 EP disclosed
US-20030050359-A1 Dental adhesive composition TOKUYAMA DENTAL CORPORATION (JP) 2003-03-13 US disclosed
EP-1249221-A1 DENTAL ADHESIVE COMPOSITION Tokuyama Dental Corporation (JP) 2002-10-16 EP disclosed
US-20020132951-A1 Dental catalyst for chemical polymerization and use thereof TOKUYAMA CORPORATION 2002-09-19 US disclosed
EP-1190695-A1 Catalyst for chemical polymerization of dental materials TOKUYAMA CORPORATION (JP) 2002-03-27 EP disclosed
US-5866631-A POLYMERIZABLE MONOMER CONTAINING AN ACIDIC GROUP, WATER, ARYL BORATE AND TRANSITION METAL COMPOUND. TOKUYAMA CORPORATION (JP) 1999-02-02 US disclosed
EP-0811368-A1 DENTAL PRIMER COMPOSITION AND POLYMERIZATION CATALYST TOKUYAMA CORPORATION (JP) 1997-12-10 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040006154-A1 Deantal catalyst for chemical polymerization and use thereof MPO, DBN1, BRD1 CNR2 4597/4885CNR1 4634/4885CA12 1144/4885
US-11607370-B2 Dental composition ITGAL, ITGA1, ITGB3 CNR2 4581/4885CNR1 4309/4885CA12 1439/4885
US-11866590-B2 Diisocyanate-based radical polymerizable silane coupling compound having an urethane bond CAD, DCLRE1A, STIM1 CNR2 3007/4885CNR1 3027/4885CA12 1173/4885
US-20030050359-A1 Dental adhesive composition CAD, ASIC1, CD44 CNR2 4860/4885CNR1 4852/4885CA12 2721/4885
US-20230040426-A1 DENTAL RESTORATION MATERIAL COMPOSITION CAD, MAT2B, RER1 CNR2 3506/4885CNR1 3771/4885CA12 3372/4885
US-20240164993-A1 ORGANOSILICON COMPOUND AND DENTAL COMPOSITION CONTAINING SAME MSL1, ITGA1, ASH2L CNR2 2893/4885CNR1 2380/4885CA12 1769/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.