Known targets — ChEMBL curated mechanism
ACHEBDKRB2CHRM1CHRM2CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNGGUCY1A1GUCY1A2GUCY1B1GUCY1B2NAMPTPTAFRSLC10A2SLC6A2SLC6A3TACR1dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of Hydrochloric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE known ✓ | P22303 | 3/20 | 0.47 |
| ▸ | PRKD3 | O94806 | 2/20 | 0.65 |
| ▸ | PRKCG | P05129 | 2/20 | 0.65 |
| ▸ | PRKCB | P05771 | 2/20 | 0.65 |
| ▸ | PRKCA | P17252 | 2/20 | 0.65 |
| ▸ | PRKCH | P24723 | 2/20 | 0.65 |
| ▸ | PRKCI | P41743 | 2/20 | 0.65 |
| ▸ | PRKCE | Q02156 | 2/20 | 0.65 |
| ▸ | PRKCQ | Q04759 | 2/20 | 0.65 |
| ▸ | PRKCZ | Q05513 | 2/20 | 0.65 |
| ▸ | PRKCD | Q05655 | 2/20 | 0.65 |
| ▸ | PRKD1 | Q15139 | 2/20 | 0.65 |
| ▸ | DNM1 | Q05193 | 6/20 | 0.58 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | AKT1 | P31749 | 2/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.52 |
| ▸ | CDC25A | P30304 | 1/20 | 0.52 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.52 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL25306967 | 1.00 | PRKD3 (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL28622332 | 1.00 | PRKD3 (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL597002 | 1.00 | PRKD3 (0.65) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Water SCHEMBL29707870 | 0.98 | PRKD3 (0.62) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| Hydrochloric Acid SCHEMBL253903 | 0.98 | PRKD3 (0.61) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL5447359 | 0.98 | PRKD3 (0.67) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8855786 | 0.98 | PRKD3 (0.67) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8855744 | 0.98 | PRKD3 (0.67) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8855768 | 0.98 | PRKD3 (0.67) | PRKD3PRKCGPRKCBPRKCAPRKCH | |
| SCHEMBL8855806 | 0.98 | PRKD3 (0.67) | PRKD3PRKCGPRKCBPRKCAPRKCH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9511008-B2 | Conditioning composition for keratin fibres and its use | KAO GERMANY GMBH (DE) | 2016-12-06 | — | — | US | claimed |
| WO-2005018631-A1 | USE OF CHOLINE DERIVATIVES FOR MEMORY, LEARNING AND COGNITION | PATEL HASMUKH (US) | 2005-03-03 | — | — | WO | claimed |
| US-20050038116-A1 | Novel class of compounds (Choline derivatives, esp. Stearyl Choline Cloride and other salts) for the treatment of Alzheimer's disease, Down syndrome and central (and/or peripheral) nervous system and memory related disorders or for enhancements | PATEL HASMUKH B (US) | 2005-02-17 | — | — | US | claimed |
| US-20260083660-A1 | HAIR TREATMENT AGENT, OR FIBER TREATMENT AGENT FOR HEADWEAR PRODUCTS | KAO CORPORATION (JP) | 2026-03-26 | — | — | US | disclosed |
| US-12521326-B2 | Aerosol composition | KAO CORPORATION (JP) | 2026-01-13 | — | — | US | disclosed |
| US-20250345263-A1 | PRODUCTION METHOD FOR AQUEOUS COMPOSITION | KAO CORPORATION (JP) | 2025-11-13 | — | — | US | disclosed |
| US-12409128-B2 | Shampoo comprising a silicone blend and a ternary surfactant mixture | KAO CORPORATION (JP) | 2025-09-09 | — | — | US | disclosed |
| US-12384985-B2 | Detergent | KAO CORPORATION (JP) | 2025-08-12 | — | — | US | disclosed |
| EP-4568751-A1 | METHOD FOR TREATING HAIR | Kao Corporation (JP) | 2025-06-18 | — | — | EP | disclosed |
| US-20250186330-A1 | COSMETIC MATERIAL COMPOSITION AND FIBER TREATMENT COMPOSITION FOR HEAD DECORATION PRODUCTS | KAO CORPORATION (JP) | 2025-06-12 | — | — | US | disclosed |
| US-20250152484-A1 | OIL-IN-WATER EMULSION SKIN PREPARATION FOR EXTERNAL USE | KAO CORPORATION (JP) | 2025-05-15 | — | — | US | disclosed |
| US-20070166272-A1 | HAIR COSMETIC COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME | KAO CORPORATION (JP) | 2007-07-19 | — | — | US | disclosed |
| EP-1808157-A1 | Hair cosmetic compositions and process for producing the same | Kao Corporation (JP) | 2007-07-18 | — | — | EP | disclosed |
| US-20060205815-A1 | Choline esters useful for the treatment of cognitive dysfunctions and enhancement of memory, learning and cognition | PATEL HASMUKH B | 2006-09-14 | — | — | US | disclosed |
| US-20060205815-A1 | Choline esters useful for the treatment of cognitive dysfunctions and enhancement of memory, learning and cognition | PATEL HASMUKH B | 2006-09-14 | — | — | US | disclosed |
| EP-1660434-A1 | CHOLINE ESTERS USEFUL FOR THE TREATMENT OF COGNITIVE DYSFUNCTIONS AND ENHANCEMENT OF MEMORY, LEARNING AND COGNITION | PATEL, Hasmukh B. (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1660434-A1 | CHOLINE ESTERS USEFUL FOR THE TREATMENT OF COGNITIVE DYSFUNCTIONS AND ENHANCEMENT OF MEMORY, LEARNING AND COGNITION | PATEL, Hasmukh B. (US) | 2006-05-31 | — | — | EP | disclosed |
| WO-2005019157-A1 | CHOLINE ESTERS USEFUL FOR THE TREATMENT OF COGNITIVE DYSFUNCTIONS AND ENHANCEMENT OF MEMORY, LEARNING AND COGNITION | PATEL HASMUKH B (US) | 2005-03-03 | — | — | WO | disclosed |
| WO-2005019157-A1 | CHOLINE ESTERS USEFUL FOR THE TREATMENT OF COGNITIVE DYSFUNCTIONS AND ENHANCEMENT OF MEMORY, LEARNING AND COGNITION | PATEL HASMUKH B (US) | 2005-03-03 | — | — | WO | disclosed |
| WO-2005018631-A1 | USE OF CHOLINE DERIVATIVES FOR MEMORY, LEARNING AND COGNITION | PATEL HASMUKH (US) | 2005-03-03 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12409128-B2 | Shampoo comprising a silicone blend and a ternary surfactant mixture | SMURF1, SGMS1, PHOSPHO1 | ACHE 655/4885PRKD3 2515/4885PRKCG 3484/4885 |
| US-20060205815-A1 | Choline esters useful for the treatment of cognitive dysfunctions and enhancement of memory, learning and cognition | CHAT, SGMS1, SPTLC1 | ACHE 22/4885PRKD3 1367/4885PRKCG 831/4885 |
| US-20250186330-A1 | COSMETIC MATERIAL COMPOSITION AND FIBER TREATMENT COMPOSITION FOR HEAD DECORATION PRODUCTS | H1-0, DEGS1, CUTA | ACHE 1403/4885PRKD3 1008/4885PRKCG 1017/4885 |
| US-20050038116-A1 | Novel class of compounds (Choline derivatives, esp. Stearyl Choline Cloride and other salts) for the treatment of Alzheimer's disease, Down syndrome and central (and/or peripheral) nervous system and memory related disorders or for enhancements | CHAT, SGMS1, SPTLC3 | ACHE 8/4885PRKD3 590/4885PRKCG 1195/4885 |
| US-20260083660-A1 | HAIR TREATMENT AGENT, OR FIBER TREATMENT AGENT FOR HEADWEAR PRODUCTS | POLR1C, COL1A1, COL2A1 | ACHE 4803/4885PRKD3 4364/4885PRKCG 4829/4885 |
| US-20070166272-A1 | HAIR COSMETIC COMPOSITIONS AND PROCESS FOR PRODUCING THE SAME | CUTA, SHH, POLR1C | ACHE 1722/4885PRKD3 2573/4885PRKCG 1193/4885 |
| US-20250152484-A1 | OIL-IN-WATER EMULSION SKIN PREPARATION FOR EXTERNAL USE | CUTA, NAPEPLD, LIPA | ACHE 2599/4885PRKD3 1641/4885PRKCG 451/4885 |
| US-20250345263-A1 | PRODUCTION METHOD FOR AQUEOUS COMPOSITION | PHOSPHO1, PARG, NAPEPLD | ACHE 4366/4885PRKD3 1688/4885PRKCG 334/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.