Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 7/20 | 0.48 |
| ▸ | TSHR | P16473 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | LIPE | Q05469 | 6/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.46 |
| ▸ | USP2 | O75604 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10512960 | 0.86 | TACR1 (0.52) | MAPK1ALDH1A1TP53CYP2C19CYP1A2 | |
| SCHEMBL10514541 | 0.86 | THRB (0.41) | ALDH1A1TP53 | |
| SCHEMBL10515488 | 0.83 | TACR1 (0.49) | MAPK1ALDH1A1TP53CYP2C19CYP1A2 | |
| SCHEMBL10515742 | 0.83 | OPRM1 (0.44) | — | |
| SCHEMBL10513647 | 0.83 | TRPM8 (0.43) | CYP3A4TRPV1USP2 | |
| SCHEMBL10515329 | 0.82 | TRPM8 (0.57) | CYP3A4TRPV1 | |
| SCHEMBL11224032 | 0.79 | DRD2 (0.50) | — | |
| SCHEMBL10516337 | 0.76 | TACR1 (0.52) | CYP3A4ALDH1A1CYP2C19CYP1A2USP2 | |
| SCHEMBL11159629 | 0.75 | APP (0.55) | TSHRSMN1; SMN2ALDH1A1 | |
| SCHEMBL21616684 | 0.75 | ALDH1A1 (0.71) | TSHRSMN1; SMN2ALDH1A1TRPV1LIPE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4031221-A | ANALGESICS, TRANQUILIZERS, INDOLE COMPOUNDS | AMERICAN HOECHST CORPORATION (US) | 1977-06-21 | — | — | US | disclosed |