Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 6/20 | 0.39 |
| ▸ | ADRB1 | P08588 | 2/20 | 0.39 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11842180 | 0.98 | ADRB2 (0.38) | ADRB2ADRB1ADRB3PTGS2OPRK1 | |
| SCHEMBL11844944 | 0.81 | ADRB2 (0.55) | ADRB2ADRB1ADRB3PTGS2OPRK1 | |
| Hydrochloric Acid SCHEMBL11853153 | 0.80 | KDM4E (0.54) | ADRB2ADRB1ADRB3PTGS2OPRK1 | |
| SCHEMBL12380944 | 0.74 | GABRA1 (0.46) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL11850533 | 0.72 | ADRB1 (0.68) | ADRB2ADRB1ADRB3ADRA2AADRA2B | |
| SCHEMBL11841864 | 0.70 | TDP1 (0.35) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL2760850 | 0.68 | ADRA2A (0.66) | ADRB2ADRB1ADRB3PTGS2ADRA2A | |
| SCHEMBL11849763 | 0.67 | METAP2 (0.33) | ADRB2ADRA2AADRA2BADRA2CADRA1A | |
| SCHEMBL2250 | 0.66 | ADRA2A (0.61) | ADRB2ADRB1ADRB3PTGS2ADRA2A | |
| SCHEMBL19426175 | 0.65 | FFAR2 (0.34) | ADRA2AADRA2BADRA2CADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-3976695-A | Halogen substituted α-(aminoalkyl)-3,4-dihydroxybenzyl alcohols | SMITHKLINE CORPORATION (US) | 1976-08-24 | — | — | US | claimed |