Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.53 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.53 |
| ▸ | SRD5A2 | P31213 | 3/20 | 0.52 |
| ▸ | CA1 | P00915 | 2/20 | 0.50 |
| ▸ | CA2 | P00918 | 2/20 | 0.50 |
| ▸ | CA12 | O43570 | 1/20 | 0.50 |
| ▸ | CA3 | P07451 | 1/20 | 0.50 |
| ▸ | TYR | P14679 | 1/20 | 0.50 |
| ▸ | DRD1 | P21728 | 1/20 | 0.50 |
| ▸ | CA4 | P22748 | 1/20 | 0.50 |
| ▸ | CA6 | P23280 | 1/20 | 0.50 |
| ▸ | CA5A | P35218 | 1/20 | 0.50 |
| ▸ | CA7 | P43166 | 1/20 | 0.50 |
| ▸ | CA9 | Q16790 | 1/20 | 0.50 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.50 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.50 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.48 |
| ▸ | BAD | Q92934 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Terephthalic Acid SCHEMBL1010632 | 0.81 | TSHR (0.92) | TSHRTP53SRD5A2CA1CA2 | |
| SCHEMBL16161046 | 0.80 | AKR1C3 (0.41) | TSHRTP53AKR1C3AKR1C2CA1 | |
| SCHEMBL21585246 | 0.79 | ALDH1A1 (0.61) | TSHRTP53AKR1C3AKR1C2SRD5A2 | |
| SCHEMBL8045036 | 0.78 | ALDH1A1 (0.43) | TSHRTP53AKR1C3AKR1C2CA1 | |
| SCHEMBL3539246 | 0.78 | PARP10 (0.48) | TSHRAKR1C3AKR1C2CA1CA2 | |
| SCHEMBL8737307 | 0.78 | MAPT (0.48) | AKR1C3AKR1C2ALDH1A1SMN1; SMN2 | |
| Terephthalic Acid SCHEMBL175823 | 0.78 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL2511919 | 0.78 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL5053781 | 0.78 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 | |
| Terephthalic Acid SCHEMBL1655 | 0.78 | TSHR (1.00) | TSHRTP53SRD5A2CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110770271-B | Method for preparing functionalized fluorinated monomers, fluorinated monomers and compositions for preparing same | 埃特纳科技有限公司 | 2023-04-18 | — | — | CN | claimed |
| US-20090036704-A1 | Process for Preparing 4-Pentafluorosulfanylbenzoylguanidines | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2009-02-05 | — | — | US | claimed |
| US-7449594-B2 | Process for preparing 4-pentafluorosulfanylbenzoylguanidines | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2008-11-11 | — | — | US | claimed |
| US-20070106094-A1 | Process For Preparing 4-Pentafluorosulfanylbenzoylguanidines | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-05-10 | — | — | US | claimed |
| US-7126026-B2 | Process for preparing 4-pentafluorosulfanylbenzoylguanidines | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2006-10-24 | — | — | US | claimed |
| US-20050131070-A1 | Process for preparing 4-pentafluorosulfanylbenzoylguanidines | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2005-06-16 | — | — | US | claimed |
| EP-4558500-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | Sanofi (FR) | 2025-05-28 | — | — | EP | disclosed |
| CN-118791407-A | Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives | 奥索生物公司 | 2024-10-18 | — | — | CN | disclosed |
| CN-118638096-A | Sulfinylamino group benzamide and process for preparing same Sulfonylamino benzamide derivatives | 奥索生物公司 | 2024-09-13 | — | — | CN | disclosed |
| CN-112204008-B | Sulfonylaminobenzamides and sulfonylaminobenzamide derivatives | 奥索生物公司 | 2024-07-05 | — | — | CN | disclosed |
| WO-2024017977-A1 | IMIDAZOPYRIDINE COMPOUNDS, PREPARATION THEREOF AND THERAPEUTIC USES THEREOF | SANOFI (FR) | 2024-01-25 | — | — | WO | disclosed |
| EP-3796975-B1 | SULFONYLAMINOBENZAMIDE DERIVATIVES | ORSOBIO INC (US) | 2023-08-30 | — | — | EP | disclosed |
| US-11390610-B2 | Piperazine derivatives as MAGL inhibitors | HOFFMANN-LA ROCHE INC. (US) | 2022-07-19 | — | — | US | disclosed |
| US-20070179191-A1 | OXADIAZOLONES AND DERIVATIVES THEREOF AS PPAR DELTA AGONISTS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2007-08-02 | — | — | US | disclosed |
| EP-1740583-A1 | OXADIAZOLONE DERIVATIVES AS PPAR DELTA AGONISTS | Sanofi-Aventis Deutschland GmbH (DE) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005097786-A1 | OXADIAZOLONE DERIVATIVES AS PPAR DELTA AGONISTS | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2005-10-20 | — | — | WO | disclosed |
| US-20030216476-A1 | Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them | AVENTIS PHARMA DEUTSHCHLAND GMBH (DE) | 2003-11-20 | — | — | US | disclosed |
| US-6140528-A | ALKYL PENTAFLUOROSULFANYL-SUBSTITUTED-BENZOATES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-10-31 | — | — | US | disclosed |
| US-6013805-A | USED AS HERBICIDES | RHONE-POULENC AGRICULTURE LTD (GB) | 2000-01-11 | — | — | US | disclosed |
| US-5849928-A | Herbicidal isoxazole and 2-cyano-1,3-dione compounds | RHONE-POULENC AGRICULTURE LIMITED (GB) | 1998-12-15 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070179191-A1 | OXADIAZOLONES AND DERIVATIVES THEREOF AS PPAR DELTA AGONISTS | PPARD, PPARA, PPARG | TSHR 680/4885TP53 3150/4885AKR1C3 1404/4885 |
| US-11390610-B2 | Piperazine derivatives as MAGL inhibitors | MAGI3, PYM1, MAG | TSHR 3028/4885TP53 3649/4885AKR1C3 2867/4885 |
| US-20090036704-A1 | Process for Preparing 4-Pentafluorosulfanylbenzoylguanidines | NHERF1, SLC9A1, SLC5A1 | TSHR 465/4885TP53 4774/4885AKR1C3 1284/4885 |
| US-20050131070-A1 | Process for preparing 4-pentafluorosulfanylbenzoylguanidines | NHERF1, SLC9A1, SLC5A1 | TSHR 465/4885TP53 4774/4885AKR1C3 1284/4885 |
| US-20030216476-A1 | Pentafluorosulfanylbenzoylguanidines, processes for their preparation, their use as medicaments or diagnostic aids, and medicaments comprising them | TNNI3, TNNT2, SDHB | TSHR 2514/4885TP53 3255/4885AKR1C3 2694/4885 |
| US-20070106094-A1 | Process For Preparing 4-Pentafluorosulfanylbenzoylguanidines | PAH, NCEH1, PNMT | TSHR 376/4885TP53 4322/4885AKR1C3 2080/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.