Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 7/20 | 0.67 |
| ▸ | HTR1A | P08908 | 6/20 | 0.67 |
| ▸ | DRD2 | P14416 | 6/20 | 0.67 |
| ▸ | ADRA2C | P18825 | 6/20 | 0.67 |
| ▸ | SLC6A2 | P23975 | 6/20 | 0.67 |
| ▸ | HTR2A | P28223 | 6/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 6/20 | 0.67 |
| ▸ | ADRA1A | P35348 | 6/20 | 0.67 |
| ▸ | DRD3 | P35462 | 6/20 | 0.67 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.67 |
| ▸ | KCNH2 | Q12809 | 6/20 | 0.67 |
| ▸ | ADRA2A | P08913 | 5/20 | 0.67 |
| ▸ | DRD1 | P21728 | 5/20 | 0.67 |
| ▸ | ADRA2B | P18089 | 5/20 | 0.67 |
| ▸ | HTR2B | P41595 | 4/20 | 0.67 |
| ▸ | HRH3 | Q9Y5N1 | 4/20 | 0.67 |
| ▸ | MLNR | O43193 | 2/20 | 0.67 |
| ▸ | ESR1 | P03372 | 2/20 | 0.67 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.67 |
| ▸ | KDM1A | O60341 | 3/20 | 0.65 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butaperazine SCHEMBL28086241 | 1.00 | HRH1 (0.67) | HRH1HTR1ADRD2ADRA2CSLC6A2 | |
| Butaperazine SCHEMBL29710903 | 1.00 | HRH1 (0.67) | HRH1HTR1ADRD2ADRA2CSLC6A2 | |
| Butaperazine SCHEMBL31153317 | 1.00 | HRH1 (0.67) | HRH1HTR1ADRD2ADRA2CSLC6A2 | |
| Butaperazine SCHEMBL120744 | 0.94 | LMNA (0.72) | HRH1HTR1ADRD2ADRA2CSLC6A2 | |
| Butaperazine SCHEMBL120743 | 0.94 | LMNA (0.72) | HRH1HTR1ADRD2ADRA2CSLC6A2 | |
| Thioproperazine SCHEMBL13723252 | 0.90 | DRD3 (0.79) | HRH1HTR1ADRD2ADRA2CSLC6A2 | |
| SCHEMBL18309819 | 0.88 | HRH1 (0.69) | HRH1HTR1ADRD2ADRA2CSLC6A2 | |
| SCHEMBL141601 | 0.87 | HTR1A (0.86) | HRH1HTR1ADRD2ADRA2CSLC6A2 | |
| SCHEMBL26837052 | 0.85 | HRH1 (0.69) | HRH1HTR1ADRD2ADRA2CSLC6A2 | |
| Carphenazine SCHEMBL1458434 | 0.84 | HRH1 (0.81) | HRH1HTR1ADRD2ADRA2CSLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1881 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4618973-A1 | METHODS OF SWITCHING NEUROPSYCHIATRIC MEDICATIONS USING ULOTARONT | Sumitomo Pharma America, Inc. (US) | 2025-09-24 | — | — | EP | claimed |
| US-20250179064-A1 | BENZOQUINOLONE INHIBITORS OF VMAT2 | AUSPEX PHARMACEUTICALS LLC | 2025-06-05 | — | — | US | claimed |
| US-12178804-B2 | Salts of cycloserine compounds and applications thereof | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2024-12-31 | — | — | US | claimed |
| WO-2024107681-A1 | METHODS OF SWITCHING NEUROPSYCHIATRIC MEDICATIONS USING ULOTARONT | SUMITOMO PHARMA AMERICA, INC. (US) | 2024-05-23 | — | — | WO | claimed |
| EP-3529229-B1 | POLYMORPHIC FORMS OF SODIUM BENZOATE AND USES THEREOF | SYNEURX INT TAIWAN CORP (TW) | 2024-04-17 | — | — | EP | claimed |
| US-20240000810-A1 | USE OF CANNABINOIDS IN THE TREATMENT OF TOURETTE SYNDROME AND TIC DISORDERS | Orcosa Inc. (US) | 2024-01-04 | — | — | US | claimed |
| US-20230321073-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION | Response IP Holding Company, LLC (US) | 2023-10-12 | — | — | US | claimed |
| US-20230218623-A1 | SALTS OF NEUROCEUTICALS AND USES THEREOF | SYNEURX INTERNATIONAL (TAIWAN) CORP. (TW) | 2023-07-13 | — | — | US | claimed |
| EP-4192579-A2 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION | Response IP Holding Company, LLC (US) | 2023-06-14 | — | — | EP | claimed |
| EP-4146656-A1 | SALTS OF NEUROCEUTICALS AND USES THEREOF | Syneurx International (Taiwan) Corp. (TW) | 2023-03-15 | — | — | EP | claimed |
| EP-0174342-B1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES | UNIVERSITY OF FLORIDA (US) | 1989-12-20 | — | — | EP | claimed |
| EP-0263873-A4 | ANTI-PATHOGENIC BLOOD COLLECTION SYSTEM AND METHOD. | AL-SIOUFI HABIB | 1989-07-11 | — | — | EP | claimed |
| EP-0263873-A1 | ANTI-PATHOGENIC BLOOD COLLECTION SYSTEM AND METHOD | AL-SIOUFI, Habib (US) | 1988-04-20 | — | — | EP | claimed |
| WO-1987006119-A1 | ANTI-PATHOGENIC BLOOD COLLECTION SYSTEM AND METHOD | AL SIOUFI HABIB | 1987-10-22 | — | — | WO | claimed |
| EP-0180364-A2 | Pharmaceutical compositions containing phenothiazines | RECKITT AND COLMAN PRODUCTS LIMITED (GB) | 1986-05-07 | — | — | EP | claimed |
| EP-0174342-A1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES. | UNIV FLORIDA (US) | 1986-03-19 | — | — | EP | claimed |
| WO-1985003937-A1 | BRAIN-SPECIFIC ANALOGUES OF CENTRALLY ACTING AMINES | UNIVERSITY OF FLORIDA (US) | 1985-09-12 | — | — | WO | claimed |
| US-4407800-A | TRYPANOCIDES | UNIVERSITY OF VIRGINIA ALUMNI PATENTS FOUNDATION (US) | 1983-10-04 | — | — | US | claimed |
| US-4249003-A | Process for polycyclic amines | AKTIEBOLAGET LEO (SE) | 1981-02-03 | — | — | US | claimed |
| US-4175119-A | Composition and method to prevent accidental and intentional overdosage with psychoactive drugs | PORTER GARRY L | 1979-11-20 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250179064-A1 | BENZOQUINOLONE INHIBITORS OF VMAT2 | ACAT2, CPT1A, SLC18A2 | HRH1 3242/4885HTR1A 747/4885DRD2 2127/4885 |
| US-20230321073-A1 | COMPOSITIONS AND METHODS FOR TREATING METABOLIC DYSREGULATION | LIPC, CPT1A, CETP | HRH1 4797/4885HTR1A 3890/4885DRD2 4836/4885 |
| US-20230218623-A1 | SALTS OF NEUROCEUTICALS AND USES THEREOF | SLC1A2, GABRA6, GABRA2 | HRH1 1889/4885HTR1A 932/4885DRD2 1923/4885 |
| US-12178804-B2 | Salts of cycloserine compounds and applications thereof | TST, RIMKLA, PSPH | HRH1 2093/4885HTR1A 336/4885DRD2 930/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.