Sugi Predict

Sugi Predict / Compounds / SCHEMBL247419

SCHEMBL247419

SCHEMBL247419

CC1=C(N2CCCC2)C(=O)OC1

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ L3MBTL1 Q9Y468 5/20 0.36
▸ ALDH1A1 P00352 6/20 0.34
▸ HPGD P15428 4/20 0.34
▸ MAPT P10636 4/20 0.34
▸ ALOX15 P16050 4/20 0.34
▸ TSHR P16473 2/20 0.34
▸ MAPK1 P28482 2/20 0.34
▸ POLB P06746 2/20 0.34
▸ NPC1 O15118 3/20 0.33
▸ RAB9A P51151 2/20 0.33
▸ APAF1 O14727 2/20 0.33
▸ GAA P10253 1/20 0.32
▸ LMNA P02545 3/20 0.32
▸ TDP1 Q9NUW8 2/20 0.31
▸ SMN1; SMN2 Q16637 2/20 0.31
▸ NPSR1 Q6W5P4 1/20 0.31
▸ KCNJ1 P48048 1/20 0.31
▸ KCNH2 Q12809 1/20 0.31
▸ HSD17B10 Q99714 4/20 0.31
▸ KDM4E B2RXH2 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28059928 1.00 L3MBTL1 (0.36) L3MBTL1ALDH1A1HPGDMAPTALOX15
SCHEMBL4589801 0.75 NPC1 (0.43) L3MBTL1ALDH1A1NPC1RAB9ALMNA
SCHEMBL981116 0.74 — —
SCHEMBL27897051 0.71 MAPT (0.40) ALDH1A1MAPTLMNA
SCHEMBL469465 0.71 TYR (0.43) L3MBTL1ALDH1A1HPGDMAPTALOX15
SCHEMBL120459 0.70 SMN1; SMN2 (0.40) L3MBTL1ALDH1A1HPGDMAPTALOX15
SCHEMBL4582486 0.68 SMN1; SMN2 (0.36) L3MBTL1ALDH1A1HPGDMAPTALOX15
SCHEMBL6129238 0.68 SMN1; SMN2 (0.43) L3MBTL1ALDH1A1HPGDMAPTALOX15
SCHEMBL10446742 0.67 APAF1 (0.39) L3MBTL1ALDH1A1HPGDMAPTALOX15
SCHEMBL469461 0.64 L3MBTL1 (0.37) L3MBTL1ALDH1A1HPGDMAPTALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 502 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118984825-A Novel cooling agent and preparation containing same 西姆莱斯股份公司 2024-11-19 — — CN claimed
EP-4452941-A1 ACTIVE INGREDIENTS WITH SIALAGOGUE AND TINGLING/FIZZY EFFECT, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2024-10-30 — — EP claimed
US-20240058259-A1 COMPOSITIONS COMPRISING ESSENTIAL OILS FIRMENICH SA (CH) 2024-02-22 — — US claimed
US-20240041726-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION CHATTEM, INC. 2024-02-08 — — US claimed
US-20240000746-A1 New Cooling Agents and Preparations Containing Them SYMRISE AG (DE) 2024-01-04 — — US claimed
EP-4268814-A2 PHARMACEUTICAL COMPOSITION FOR THE TREATMENT OF DRY EYE Universidad Miguel Hernández De Elche (ES) 2023-11-01 — — EP claimed
EP-4247791-A2 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME Symrise AG (DE) 2023-09-27 — — EP claimed
CN-116685575-A Novel cooling substances and formulations containing these cooling substances 西姆莱斯股份公司 2023-09-01 — — CN claimed
EP-4231985-A1 FOAMABLE COMPOSITION, USE THEREOF, AND PROCESS FOR ITS PREPARATION Chattem, Inc. (US) 2023-08-30 — — EP claimed
WO-2023143741-A1 NEW COOLANTS, AND PREPARATIONS CONTAINING SAME SYMRISE AG (DE) 2023-08-03 — — WO claimed
EP-1455609-A2 METHOD AND COMPOSITIONS FOR IMPARTING COOLING EFFECT TO TOBACCO PRODUCTS Vector Tobacco Inc. (US) 2004-09-15 — — EP claimed
US-20040086619-A1 Use of surfactants to solubilize water-insoluble solids in beverages PEPSICO INC. 2004-05-06 — — US claimed
WO-2004023900-A1 USE OF SURFACTANTS TO SOLUBILIZE WATER-INSOLUBLE SOLIDS IN BEVERAGES PEPSICO, INC. (US) 2004-03-25 — — WO claimed
US-20040052828-A1 Consumable product including consumable component and alpha-keto enamine derivatives NESTEC S.A. (CH) 2004-03-18 — — US claimed
WO-2004000255-A1 ANTIPERSPIRANT STICK WITH COOLING AND DRYING EFFECT COLGATE-PALMOLIVE COMPANY (US) 2003-12-31 — — WO claimed
WO-2004000254-A1 SOFT SOLID ANTIPERSPIRANT WITH COOLING AND DRYING EFFECT COLGATE-PALMOLIVE COMPANY (US) 2003-12-31 — — WO claimed
US-20030235546-A1 Cool and dry antiperspirant stick COLGATE-PALMOLIVE COMPANY 2003-12-25 — — US claimed
US-20030235545-A1 Cool and dry soft solid antiperspirant COLGATE-PALMOLIVE COMPANY 2003-12-25 — — US claimed
WO-2003053176-A2 METHOD AND COMPOSITIONS FOR IMPARTING COOLING EFFECT TO TOBACCO PRODUCTS VECTOR TOBACCO INC. (US) 2003-07-03 — — WO claimed
US-20020022039-A1 Method of using alpha-keto enamine derivatives as ingredients and products incorporating same NESTEC S.A. (CH) 2002-02-21 — — US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030235545-A1 Cool and dry soft solid antiperspirant MDH2, MDH1, DDT L3MBTL1 1381/4885ALDH1A1 1854/4885HPGD 525/4885
US-20040052828-A1 Consumable product including consumable component and alpha-keto enamine derivatives PKN2, OPRD1, PKN1 L3MBTL1 3770/4885ALDH1A1 484/4885HPGD 114/4885
US-20030235546-A1 Cool and dry antiperspirant stick SELE, DECR1, DUSP23 L3MBTL1 1046/4885ALDH1A1 2325/4885HPGD 2533/4885
US-20020022039-A1 Method of using alpha-keto enamine derivatives as ingredients and products incorporating same ECH1, KMO, PKN1 L3MBTL1 3305/4885ALDH1A1 840/4885HPGD 78/4885
US-20240000746-A1 New Cooling Agents and Preparations Containing Them TTPA, TREH, TAS2R45 L3MBTL1 4713/4885ALDH1A1 1658/4885HPGD 1155/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.