SCHEMBL12048428

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL12048301	0.96	SIGMAR1 (0.41)	SIGMAR1HSD17B1HSD17B2KDM4CCSF1R
	SCHEMBL12047919	0.96	SIGMAR1 (0.45)	SIGMAR1KDM4CCSF1REGFRDHFR
	SCHEMBL12048489	0.95	SIGMAR1 (0.41)	SIGMAR1HSD17B1HSD17B2KDM4CCSF1R
	SCHEMBL12048010	0.95	SIGMAR1 (0.41)	SIGMAR1HSD17B1HSD17B2KDM4CCSF1R
	SCHEMBL12047788	0.92	SIGMAR1 (0.44)	SIGMAR1KDM4CCSF1REGFRDHFR
	SCHEMBL12048525	0.91	HSD17B1 (0.39)	SIGMAR1HSD17B1HSD17B2KDM4CCSF1R
	SCHEMBL14672919	0.90	SIGMAR1 (0.42)	SIGMAR1HSD17B1HSD17B2DHFRCYP1A2
	SCHEMBL12048078	0.90	SIGMAR1 (0.39)	SIGMAR1HSD17B1HSD17B2KDM4CCSF1R
	SCHEMBL12048429	0.89	SIGMAR1 (0.42)	SIGMAR1DHFRCYP1A2CYP2C19CYP2A6
	SCHEMBL18069063	0.89	SIGMAR1 (0.43)	SIGMAR1HSD17B1HSD17B2DHFRCYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 37 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.