SCHEMBL1206771

SCHEMBL1206771

COc1ccccc1CCCCC(=O)O

nearest known ligand 0.59

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 1/20 0.56
LTB4R2 Q9NPC1 1/20 0.56
LMNA P02545 1/20 0.54
MTNR1A P48039 1/20 0.54
MTNR1B P49286 1/20 0.54
PTGFR P43088 1/20 0.54
PPARA Q07869 1/20 0.52
HPGD P15428 1/20 0.52
MAPT P10636 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
TAAR1 Q96RJ0 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL709396 0.98 LTB4R (0.59) LTB4RLTB4R2LMNAMTNR1AMTNR1B
SCHEMBL3264881 0.95 HPGD (0.57) LMNAMTNR1AMTNR1BPTGFRHPGD
SCHEMBL10836137 0.92 MTNR1A (0.56) LTB4RLTB4R2LMNAMTNR1AMTNR1B
SCHEMBL29590071 0.88 LMNA (0.59) LMNAMTNR1AMTNR1BHPGDTAAR1
SCHEMBL362209 0.88 LMNA (0.59) LMNAMTNR1AMTNR1BHPGDTAAR1
SCHEMBL9669777 0.86 TOP1 (0.50) LMNAMTNR1AMTNR1BPTGFRHPGD
Hydrochloric Acid SCHEMBL7413528 0.86 LMNA (0.57) LMNAMTNR1AMTNR1BHPGDTAAR1
SCHEMBL6112724 0.86 PPARA (0.52) LTB4RLTB4R2LMNAPPARAHPGD
SCHEMBL7827662 0.86 ALOX5 (0.68) LTB4RLTB4R2LMNAPPARAHPGD
SCHEMBL17315856 0.85 MTNR1A (0.56) MTNR1AMTNR1BPPARATAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO claimed
US-11253596-B2 Phenylalkylcarboxylic acid delivery agents NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) 2022-02-22 US claimed
US-20200405863-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS NOVO NORDISK A/S (DK) 2020-12-31 US claimed
EP-2114145-B1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECH INC (US) 2017-11-01 EP claimed
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS PLATINUM MONTAUR LIFE SCIENCES, LLC AND AS AGENT (KY) 2017-07-06 US claimed
CN-106456662-A Compositions of pentosan polysulfate for oral administration and methods of use thereof 奥利金制药公司 2017-02-22 CN claimed
EP-3110427-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE Urigen Pharmaceuticals, Inc. (US) 2017-01-04 EP claimed
CN-105233294-A Phenylalkylcarboxylic acid delivery agent EMISPHERE TECH INC 2016-01-13 CN claimed
WO-2015127416-A1 COMPOSITIONS OF PENTOSAN POLYSULFATE SALTS FOR ORAL ADMINISTRATION AND METHODS OF USE URIGEN PHARMACEUTICALS, INC. (US) 2015-08-27 WO claimed
US-20120258911-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2012-10-11 US claimed
US-20110046050-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2011-02-24 US claimed
CN-101616583-A Phenylalkylcarboxylic acid delivery agents EMISPHERE TECH INC 2009-12-30 CN claimed
EP-2114145-A2 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS Emisphere Technologies, Inc. (US) 2009-11-11 EP claimed
WO-2008112368-A2 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS EMISPHERE TECHNOLOGIES, INC. (US) 2008-09-18 WO claimed
WO-2025151884-A1 USE OF GLYCOSAMINOGLYCAN SULFATED POLYSACCHARIDES SUCH AS SODIUM PENTOSAN POLYSULFATE IN COMBINATION WITH PERMEATION AGENTS TO TREAT ALZHEIMER'S DISEASE PARSONS C LOWELL (US) 2025-07-17 WO disclosed
EP-3688124-B1 ESTER COMPOUNDS, LUBRICATING OIL COMPOSITIONS CONTAINING SAME AND PROCESSES FOR MAKING SAME EXXONMOBIL CHEMICAL PATENTS INC (US) 2023-10-25 EP disclosed
US-11253596-B2 Phenylalkylcarboxylic acid delivery agents NOVO NORDISK NORTH AMERICA OPERATIONS A/S (DK) 2022-02-22 US disclosed
US-20050245743-A1 Secondary amino anilinic piperidines as mch1 antagonists and uses thereof H. LUNDBECK A/S (DK) 2005-11-03 US disclosed
EP-1556351-A1 SECONDARY AMINO ANILINIC PIPERIDINES AS MCH1 ANTAGONISTS AND USES THEREOF H. Lundbeck A/S (DK) 2005-07-27 EP disclosed
WO-2004005257-A1 SECONDARY AMINO ANILINIC PIPERIDINES AS MCH1 ANTAGONISTS AND USES THEREOF H. LUNDBECK A/S (DK) 2004-01-15 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20050245743-A1 Secondary amino anilinic piperidines as mch1 antagonists and uses thereof MCHR1, MCHR2, MC1R LTB4R 1222/4885LTB4R2 974/4885LMNA 3570/4885
US-20200405863-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS PGF, LIPA, PDGFA LTB4R 172/4885LTB4R2 234/4885LMNA 868/4885
US-20110046050-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS PGF, LIPA, PDGFA LTB4R 172/4885LTB4R2 234/4885LMNA 868/4885
US-11253596-B2 Phenylalkylcarboxylic acid delivery agents PGF, LIPA, PDGFA LTB4R 172/4885LTB4R2 234/4885LMNA 868/4885
US-20170189443-A1 COMPOSITIONS AND METHODS FOR TREATMENT OF DISEASES AND CONDITIONS EMPLOYING ORAL ADMINISTRATION OF SODIUM PENTOSAN POLYSULFATE AND OTHER PENTOSAN POLYSULFATE SALTS SI, SLC20A1, SLC20A2 LTB4R 623/4885LTB4R2 557/4885LMNA 4376/4885
US-20120258911-A1 PHENYLALKYLCARBOXYLIC ACID DELIVERY AGENTS PGF, LIPA, PDGFA LTB4R 172/4885LTB4R2 234/4885LMNA 868/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.