SCHEMBL121350

SCHEMBL121350

NC[C@]1(CC(=O)O)C[C@H]2CCC[C@H]21

nearest known ligand 0.38

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 2/20 0.38
USP2 O75604 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
TSHR P16473 1/20 0.38
BLM P54132 1/20 0.38
CACNA2D1 P54289 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HSD11B1 P28845 1/20 0.30
POLB P06746 1/20 0.30
PEPD P12955 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3151603 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR
SCHEMBL3686565 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR
SCHEMBL3152635 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR
SCHEMBL13450787 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR
SCHEMBL1924296 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR
SCHEMBL14547320 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR
SCHEMBL7628296 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR
SCHEMBL3156153 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR
SCHEMBL3147308 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR
SCHEMBL21622002 1.00 CYP1A2 (0.38) CYP1A2USP2ALDH1A1LMNATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 794 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12350379-B2 Extended release pharmaceutical formulation and methods of treatment DOUGLAS PHARMACETICALS LTD (NZ) 2025-07-08 US claimed
US-20220347104-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION AND METHODS OF TREATMENT DOUGLAS PHARMACEUTICALS LTD. (NZ) 2022-11-03 US claimed
US-11471416-B2 Extended release pharmaceutical formulation and methods of treatment DOUGLAS PHARMACEUTICALS, LTD. (NZ) 2022-10-18 US claimed
US-20200323795-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION AND METHODS OF TREATMENT UNIVERSITY OF OTAGO (NZ) 2020-10-15 US claimed
US-10744094-B2 Extended release pharmaceutical formulation DOUGLAS PHARMACEUTICALS, LTD. (NZ) 2020-08-18 US claimed
US-20190224127-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION DOUGLAS PHARMACEUTICALS, LTD. (NZ) 2019-07-25 US claimed
US-20190105276-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION DOUGLAS PHARMACEUTICALS, LTD. (NZ) 2019-04-11 US claimed
EP-2575798-B1 GASTRORETENTIVE DOSAGE FORMS OF GABA ANALOGS RUBICON RES PRIVATE LTD (IN) 2017-08-09 EP claimed
EP-2175728-B1 SODIUM CHANNEL INHIBITORS ICAGEN INC (US) 2014-09-10 EP claimed
US-20140206670-A1 COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS PFIZER INC. (US) 2014-07-24 US claimed
US-20050043407-A1 Pharmaceutical composition for the prevention and treatment of addiction in a mammal PFIZER INC 2005-02-24 US claimed
US-20050043406-A1 Pharmaceutical composition for the treatment of obesity or to facilitate or promote weight loss PFIZER INC 2005-02-24 US claimed
US-20040176456-A1 Method of treatment for sexual dysfunction TAYLOR CHARLES PRICE (US) 2004-09-09 US claimed
US-20040157847-A1 Synergistic combinations FIELD MARK JOHN (GB) 2004-08-12 US claimed
US-20040143014-A1 Therapeutic use of alpha-2-delta ligands PFIZER INC 2004-07-22 US claimed
US-20040116525-A1 Cyclic nitromethyl acetic acid derivatives DERRICK ANDREW MICHAEL (GB) 2004-06-17 US claimed
US-20040092522-A1 Synergistic combinations FIELD MARK JOHN (GB) 2004-05-13 US claimed
US-20040092591-A1 Therapeutic use of fused bicyclic or tricyclic amino acids BLAKEMORE DAVID CLIVE (GB) 2004-05-13 US claimed
US-6596900-B2 Brain, nervous system, neurodegenerative, gastrointestinal, sleep, rheumatic, and psychological disorders; analgesics, antiepileptic agents PFIZER INC 2003-07-22 US claimed
US-20030078300-A1 Fused bicyclic or tricyclic amino acids PFIZER INC. 2003-04-24 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040176456-A1 Method of treatment for sexual dysfunction SHBG, CHRND, ADRB2 CYP1A2 1173/4885USP2 2021/4885ALDH1A1 1007/4885
US-20030078300-A1 Fused bicyclic or tricyclic amino acids AADAT, SLC1A2, BCAT1 CYP1A2 966/4885USP2 4035/4885ALDH1A1 1302/4885
US-20200323795-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION AND METHODS OF TREATMENT CRH, HTR5A, NPY5R CYP1A2 772/4885USP2 1206/4885ALDH1A1 2863/4885
US-20220347104-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION AND METHODS OF TREATMENT CRH, HTR5A, NPY5R CYP1A2 772/4885USP2 1206/4885ALDH1A1 2863/4885
US-20040092522-A1 Synergistic combinations PDE2A, PDE1B, PDE1A CYP1A2 1219/4885USP2 2446/4885ALDH1A1 1358/4885
US-20040143014-A1 Therapeutic use of alpha-2-delta ligands CHRND, CHRNG, CHRNE CYP1A2 1702/4885USP2 2312/4885ALDH1A1 1176/4885
US-11471416-B2 Extended release pharmaceutical formulation and methods of treatment CRH, HTR5A, NPY5R CYP1A2 772/4885USP2 1206/4885ALDH1A1 2863/4885
US-20040092591-A1 Therapeutic use of fused bicyclic or tricyclic amino acids BCAT1, BCAT2, AADAT CYP1A2 2278/4885USP2 3447/4885ALDH1A1 3565/4885
US-12350379-B2 Extended release pharmaceutical formulation and methods of treatment CRH, HTR5A, NPY5R CYP1A2 772/4885USP2 1206/4885ALDH1A1 2863/4885
US-20190224127-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION CRH, HTR5A, HTR6 CYP1A2 538/4885USP2 711/4885ALDH1A1 1356/4885
US-10744094-B2 Extended release pharmaceutical formulation CRH, HTR5A, HTR6 CYP1A2 538/4885USP2 711/4885ALDH1A1 1356/4885
US-20140206670-A1 COMBINATIONS COMPRISING ALPHA-2-DELTA LIGANDS SLC6A2, OPRD1, ADRB2 CYP1A2 1017/4885USP2 4154/4885ALDH1A1 1636/4885
US-20190105276-A1 EXTENDED RELEASE PHARMACEUTICAL FORMULATION CRH, HTR5A, HTR6 CYP1A2 538/4885USP2 711/4885ALDH1A1 1356/4885
US-20040157847-A1 Synergistic combinations PDE2A, PDE1B, PDE1A CYP1A2 1219/4885USP2 2446/4885ALDH1A1 1358/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.