SCHEMBL121630

SCHEMBL121630

Fc1ccc(CBr)c(Cl)c1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.41
SMN1; SMN2 Q16637 4/20 0.41
CYP1A2 P05177 2/20 0.41
CYP2C19 P33261 2/20 0.41
RAB9A P51151 2/20 0.41
ALOX15 P16050 2/20 0.41
HSD17B10 Q99714 2/20 0.41
NPC1 O15118 1/20 0.41
CRHBP P24387 1/20 0.41
CRHR2 Q13324 1/20 0.41
GRM2 Q14416 1/20 0.41
SLC6A4 P31645 2/20 0.40
SLC6A2 P23975 1/20 0.40
P2RX7 Q99572 4/20 0.40
KDM4E B2RXH2 2/20 0.40
MEN1 O00255 1/20 0.40
CYP3A4 P08684 1/20 0.40
CYP2D6 P10635 1/20 0.40
MAPT P10636 1/20 0.40
CYP2C9 P11712 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29569492 1.00 ALDH1A1 (0.41) ALDH1A1SMN1; SMN2CYP1A2CYP2C19RAB9A
SCHEMBL3121724 0.83 ALDH1A1 (0.40) ALDH1A1SMN1; SMN2CYP1A2CYP2C19RAB9A
SCHEMBL189219 0.82 HTR2A (0.39) ALDH1A1CYP1A2CYP2C19SLC6A4SLC6A2
SCHEMBL11027381 0.80 HTR2A (0.38) ALDH1A1CYP1A2CYP2C19SLC6A4SLC6A2
SCHEMBL4371661 0.79 HTR2A (0.44) SLC6A4HTR2A
SCHEMBL14774694 0.79 PTGER1 (0.48) ALDH1A1SMN1; SMN2CYP1A2CYP2C19RAB9A
SCHEMBL8290760 0.79 ALDH1A1 (0.42) ALDH1A1SMN1; SMN2CYP1A2CYP2C19RAB9A
SCHEMBL531667 0.79 ALDH1A1 (0.43) ALDH1A1SMN1; SMN2CYP1A2CYP2C19RAB9A
SCHEMBL3307736 0.78 IDO1 (0.40) ALDH1A1SMN1; SMN2CYP1A2SLC6A4KDM4E
SCHEMBL30149750 0.78 IDO1 (0.40) ALDH1A1SMN1; SMN2CYP1A2SLC6A4KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 596 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119912847-A Composite coating and application thereof 万华化学集团股份有限公司 2025-05-02 CN claimed
CN-122071464-A Heterocyclic compound, pharmaceutical composition thereof and application thereof 上海璎黎药业有限公司 2026-05-22 CN disclosed
US-12577257-B2 Heterocyclic compounds HOFFMANN-LA ROCHE INC. (US) 2026-03-17 US disclosed
US-20260007672-A1 INHIBITORS OF MPTP NRG THERAPEUTICS LTD (GB) 2026-01-08 US disclosed
EP-4663640-A1 XANTHINE COMPOUND AND USE THEREOF Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CN) 2025-12-17 EP disclosed
US-12491185-B2 Inhibitors of mPTP NRG THERAPEUTICS LTD (GB) 2025-12-09 US disclosed
US-20250340557-A1 PYRIMIDINE DERIVATIVE ASKA PHARMACEUTICAL CO., LTD. (JP) 2025-11-06 US disclosed
EP-4638436-A1 PRMT5 INHIBITORS AND USES THEREOF GILEAD SCIENCES, INC. (US) 2025-10-29 EP disclosed
US-20250312345-A1 NON-COVALENT INHIBITORS OF THE MAIN PROTEASE OF SARS-COV-2 AND METHODS OF USE UNIV YALE (US) 2025-10-09 US disclosed
US-12435078-B2 Pyridazinones and methods of use thereof GFB (ABC), LLC (US) 2025-10-07 US disclosed
US-6030979-A INHIBITS THE STEROL 14-REDUCTASE WHICH CATALYZES THE BIOSYNTHESIS OF CHOLESTEROL FROM LANOSTEROL; ANTICHOLESTEROL AND-LIPEMIC AGENTS HANWHA CORPORATION (CN) 2000-02-29 US disclosed
US-6028197-A ENZYME INHIBITORS INHIBITING THE STEROL 14-REDUCTASE WHICH IS INVOLVED IN THE DISTAL PATHWAY OF CHOLESTEROL BIOSYNTHESIS, AND THE USE AS ANTICHOLESTEROL AGENTS OR ANTILIPEMIC AGENTS HANWHA CORPORATION (KR) 2000-02-22 US disclosed
US-4846875-A PLANT GROWTH REGULATORS FMC CORPORATION (US) 1989-07-11 US disclosed
US-4846882-A HALOBENZYL DERIVATIVES FMC CORPORATION (US) 1989-07-11 US disclosed
CN-87100152-A The compound of weeding 1987-08-12 CN disclosed
WO-1987004049-A1 N-SUBSTITUTED TETRAHYDROPHTHALIMIDE HERBICIDAL COMPOUNDS AND INTERMEDIATES THEREFOR FMC CORPORATION (US) 1987-07-16 WO disclosed
US-4567199-A SOIL INSECTICIDES IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1986-01-28 US disclosed
EP-0057795-B1 HALOBENZYL ESTERS OF HALOALKENYLCYCLOPROPANE ACIDS, THEIR PREPARATION, COMPOSITIONS AND METHOD OF COMBATING INSECT PESTS THEREWITH IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1985-07-10 EP disclosed
US-4405357-A Herbicidal 3-isoxazolidinones and hydroxamic acids FMC CORPORATION (US) 1983-09-20 US disclosed
EP-0057795-A1 Halobenzyl esters of haloalkenylcyclopropane acids, their preparation, compositions and method of combating insect pests therewith IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1982-08-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250312345-A1 NON-COVALENT INHIBITORS OF THE MAIN PROTEASE OF SARS-COV-2 AND METHODS OF USE ACE2, ACE, TMPRSS2 ALDH1A1 1642/4885SMN1; SMN2 2957/4885CYP1A2 219/4885
US-12491185-B2 Inhibitors of mPTP PARK7, PINK1, SNCA ALDH1A1 415/4885SMN1; SMN2 1036/4885CYP1A2 378/4885
US-20250340557-A1 PYRIMIDINE DERIVATIVE PTGES, PTGS1, PTGIS ALDH1A1 136/4885SMN1; SMN2 4007/4885CYP1A2 145/4885
US-12435078-B2 Pyridazinones and methods of use thereof PDXK, ATP6V1B1, REN ALDH1A1 649/4885SMN1; SMN2 2435/4885CYP1A2 70/4885
US-20260007672-A1 INHIBITORS OF MPTP PARK7, SNCA, CYC1 ALDH1A1 176/4885SMN1; SMN2 995/4885CYP1A2 1009/4885
US-12577257-B2 Heterocyclic compounds H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16, CBR1, CBR3 ALDH1A1 1116/4885SMN1; SMN2 1111/4885CYP1A2 62/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.