Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | SLC22A12 | Q96S37 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.40 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.40 |
| ▸ | MAOA | P21397 | 2/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.40 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.40 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.40 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | HTR2C | P28335 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16558002 | 0.89 | AKR1B1 (0.43) | AKR1B1SLC22A12KMT2AADRA1AADRA2A | |
| SCHEMBL16326251 | 0.84 | AKR1B1 (0.63) | AKR1B1SLC22A12ADRA1ACYP2C9CXCL8 | |
| SCHEMBL265672 | 0.81 | CTBP2 (0.55) | L3MBTL1KMT2AMAOACYP2D6ADRA2C | |
| Methyl Alcohol SCHEMBL28233464 | 0.80 | CTBP2 (0.53) | L3MBTL1KMT2AMAOACYP2D6ADRA2C | |
| SCHEMBL8984622 | 0.80 | PNMT (0.54) | AKR1B1L3MBTL1KMT2AADRA1AMEN1 | |
| SCHEMBL2421854 | 0.79 | AKR1B1 (0.65) | AKR1B1KMT2AADRA1AADRA2AMAOA | |
| SCHEMBL6805430 | 0.79 | L3MBTL1 (0.57) | AKR1B1L3MBTL1CYP3A4LMNAMAPK1 | |
| Benzene SCHEMBL10992898 | 0.77 | L3MBTL1 (0.60) | AKR1B1L3MBTL1CYP3A4LMNAHSD17B10 | |
| SCHEMBL28094939 | 0.77 | HSP90AA1 (0.47) | AKR1B1L3MBTL1KMT2AADRA1AMAOA | |
| SCHEMBL14691047 | 0.75 | P2RX7 (0.45) | AKR1B1L3MBTL1ADRA1AMAOACXCL8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240226084-A9 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | TECHFIELDS PHARMA CO., LTD. (CN) | 2024-07-11 | — | — | US | disclosed |
| US-11857545-B2 | High penetration prodrug compositions and pharmaceutical composition thereof for treatment of pulmonary conditions | TECHFIELDS PHARMA CO., LTD. (CN) | 2024-01-02 | — | — | US | disclosed |
| US-11834388-B2 | Continuous-flow preparation method of diclofenac sodium | FUDAN UNIVERSITY (CN) | 2023-12-05 | — | — | US | disclosed |
| US-11813256-B2 | High penetration prodrug compositions and pharmaceutical compositon thereof for treatment of pulmonary conditions | PREMIER RESEARCH INTERNATIONAL, LLC | 2023-11-14 | — | — | US | disclosed |
| US-20230234911-A1 | METHOD FOR SYNTHESIZING DICLOFENAC SODIUM | FUDAN UNIVERSITY (CN) | 2023-07-27 | — | — | US | disclosed |
| US-20230192595-A1 | CONTINUOUS-FLOW PREPARATION METHOD OF DICLOFENAC SODIUM | FUDAN UNIVERSITY (CN) | 2023-06-22 | — | — | US | disclosed |
| US-20140057959-A1 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | UNIVERSIDADE ESTADUAL PAULISTA JULIO DE MESQUITA FILHO - UNESP (BR) | 2014-02-27 | — | — | US | disclosed |
| US-8569335-B2 | Compounds derived from taurine, process of their preparation and pharmaceutical compositions containing these | EMS S.A. (BR) | 2013-10-29 | — | — | US | disclosed |
| US-8026285-B2 | Control release of biologically active compounds from multi-armed oligomers | BEZWADA BIOMEDICAL, LLC (US) | 2011-09-27 | — | — | US | disclosed |
| US-20110118303-A1 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | EMS S.A. (BR) | 2011-05-19 | — | — | US | disclosed |
| US-20090076174-A1 | CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS | BEZWADA BIOMEDICAL, LLC (US) | 2009-03-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230234911-A1 | METHOD FOR SYNTHESIZING DICLOFENAC SODIUM | SULT2A1, CRYAA, AADAC | AKR1B1 1187/4885L3MBTL1 4532/4885SLC22A12 2114/4885 |
| US-20140057959-A1 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | TPMT, UTS2R, NSUN3 | AKR1B1 310/4885L3MBTL1 4668/4885SLC22A12 3203/4885 |
| US-20240226084-A9 | HIGH PENETRATION PRODRUG COMPOSITIONS AND PHARMACEUTICAL COMPOSITION THEREOF FOR TREATMENT OF PULMONARY CONDITIONS | HRH4, HCAR2, PAH | AKR1B1 461/4885L3MBTL1 4827/4885SLC22A12 290/4885 |
| US-11813256-B2 | High penetration prodrug compositions and pharmaceutical compositon thereof for treatment of pulmonary conditions | CPA3, PAH, HCAR2 | AKR1B1 597/4885L3MBTL1 4421/4885SLC22A12 421/4885 |
| US-20230192595-A1 | CONTINUOUS-FLOW PREPARATION METHOD OF DICLOFENAC SODIUM | SULT2A1, NIT2, CA2 | AKR1B1 416/4885L3MBTL1 4308/4885SLC22A12 779/4885 |
| US-20090076174-A1 | CONTROL RELEASE OF BIOLOGICALLY ACTIVE COMPOUNDS FROM MULTI-ARMED OLIGOMERS | MME, CTSA, ALG1 | AKR1B1 1747/4885L3MBTL1 3068/4885SLC22A12 4783/4885 |
| US-11834388-B2 | Continuous-flow preparation method of diclofenac sodium | SULT2A1, NIT2, CA2 | AKR1B1 429/4885L3MBTL1 4178/4885SLC22A12 806/4885 |
| US-20110118303-A1 | NOVEL COMPOUNDS DERIVED FROM TAURINE, PROCESS OF THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE | TPMT, UTS2R, NSUN3 | AKR1B1 310/4885L3MBTL1 4668/4885SLC22A12 3203/4885 |
| US-11857545-B2 | High penetration prodrug compositions and pharmaceutical composition thereof for treatment of pulmonary conditions | HRH4, HCAR2, PAH | AKR1B1 461/4885L3MBTL1 4827/4885SLC22A12 290/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.