Chlorogenic Acid

Chlorogenic Acid

SCHEMBL1228850

O=C(/C=C/c1ccc(O)c(O)c1)OC1CC(O)(C(=O)O)CC(O)C1O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AKR1B1 P15121 6/20 1.00
PTPN1 P18031 6/20 1.00
APP P05067 5/20 1.00
HSD17B10 Q99714 4/20 1.00
AKR1B10 O60218 4/20 1.00
KDM4E B2RXH2 3/20 1.00
ALDH1A1 P00352 2/20 1.00
TSHR P16473 1/20 1.00
TDP1 Q9NUW8 1/20 1.00
HDAC3 O15379 1/20 1.00
PTPN2 P17706 1/20 1.00
HDAC4 P56524 1/20 1.00
HDAC1 Q13547 1/20 1.00
HDAC7 Q8WUI4 1/20 1.00
HDAC2 Q92769 1/20 1.00
HDAC10 Q969S8 1/20 1.00
HDAC11 Q96DB2 1/20 1.00
HDAC8 Q9BY41 1/20 1.00
HDAC6 Q9UBN7 1/20 1.00
HDAC9 Q9UKV0 1/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chlorogenic Acid SCHEMBL1230489 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10
Chlorogenic Acid SCHEMBL22111591 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10
Chlorogenic Acid SCHEMBL15590670 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10
Chlorogenic Acid SCHEMBL24239743 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10
Chlorogenic Acid SCHEMBL21191546 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10
Chlorogenic Acid SCHEMBL24879283 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10
Chlorogenic Acid SCHEMBL21433650 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10
Chlorogenic Acid SCHEMBL22422499 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10
Chlorogenic Acid SCHEMBL21142437 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10
Chlorogenic Acid SCHEMBL10182527 1.00 AKR1B1 (1.00) AKR1B1PTPN1APPHSD17B10AKR1B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 112 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3169166-A1 CYCLOHEXANECARBOXYLIC ACIDS FOR SELECTIVE TASTE MASKING International Flavors & Fragrances Inc. (US) 2017-05-24 EP claimed
WO-2016209664-A1 CYCLOHEXANECARBOXYLIC ACIDS FOR SELECTIVE TASTE MASKING INTERNATIONAL FLAVORS & FRAGRANCES INC. (US) 2016-12-29 WO claimed
US-7881871-B2 Method for designing surfaces BIO-LAYER PTY LIMITED (AU) 2011-02-01 US claimed
EP-1700244-A4 A METHOD FOR DESIGNING SURFACES BIO LAYER PTY LTD (AU) 2009-07-08 EP claimed
US-20070099235-A1 Method for designing surfaces BIO-LAYER PTY LIMITED (AU) 2007-05-03 US claimed
EP-1700244-A1 A METHOD FOR DESIGNING SURFACES Bio-Layer Pty Limited (AU) 2006-09-13 EP claimed
WO-2005057462-A1 A METHOD FOR DESIGNING SURFACES BIO-LAYER PTY LIMITED (AU) 2005-06-23 WO claimed
US-20250340675-A1 NEW HYALURONIC ACID DERIVATIVES AS INNOVATIVE FILLERS WiQo S.P.A. (IT) 2025-11-06 US disclosed
WO-2025052177-A2 NOVEL COMPOSITION AND METHODS OF TREATING A NEURODEGENERATIVE DISEASE THE CHINESE UNIVERSITY OF HONG KONG (CN) 2025-03-13 WO disclosed
US-12018307-B2 Process for producing a glucuronide and genetically modified microorganisms useful in this process UTAH STATE UNIVERSITY (US) 2024-06-25 US disclosed
CN-118121637-A Preparation method and application of corynebacterium glutamicum protective nano-film based on isochlorogenic acid 陕西润能油气勘探开发有限公司 2024-06-04 CN disclosed
US-11812742-B2 Biocidal solar cell THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-11-14 US disclosed
WO-2023170311-A1 ANTI-AGING COMPOSITIONS PROGELIFE (FR) 2023-09-14 WO disclosed
WO-2002100192-A1 TASTE MODIFIERS COMPRISING A CHLOROGENIC ACID GIVAUDAN SA (CH) 2002-12-19 WO disclosed
EP-1094724-B1 USE OF A PHENOL OXIDISING ENZYME IN THE TREATMENT OF TOBACCO NOVOZYMES AS (DK) 2002-10-09 EP disclosed
US-20020051761-A1 Synthetic soil-extract materials and medicaments for herpes viruses based thereon LAUB BIOCHEMICALS CORP. 2002-05-02 US disclosed
US-20020048561-A1 Synthetic soil-extract materials and medicaments for human immunodeficiency viruses based thereon LAUB BIOCHEMICALS CORP. 2002-04-25 US disclosed
US-20020049299-A1 Oxidizing and polymerizing aromatic compounds of at least one hydroxyl and carbonyl groups or at least two hydroxyl groups; humic acids LAUB BIOCHEMICALS CORP. 2002-04-25 US disclosed
US-6298859-B1 Use of a phenol oxidizing enzyme in the treatment of tobacco NOVOZYMES A/S (DK) 2001-10-09 US disclosed
WO-2001066106-A1 A PHARMACEUTICAL COMPOSITION HAVING CHLOROGENIC ACID AS ACTIVE COMPONENT FOR PREVENTING OR TREATING THE DECLINING OF MALE REPRODUCTION CAPABILITY WOORICHEM TECH CO., LTD. (KR) 2001-09-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020049299-A1 Oxidizing and polymerizing aromatic compounds of at least one hydroxyl and carbonyl groups or at least two hydroxyl groups; humic acids HAO2, PAH, HAAO AKR1B1 2018/4885PTPN1 2372/4885APP 777/4885
US-20020048561-A1 Synthetic soil-extract materials and medicaments for human immunodeficiency viruses based thereon THEM6, SORD, OAT AKR1B1 3657/4885PTPN1 2922/4885APP 1381/4885
US-20020051761-A1 Synthetic soil-extract materials and medicaments for herpes viruses based thereon TK1, SORD, ALPP AKR1B1 3331/4885PTPN1 3166/4885APP 1352/4885
US-20250340675-A1 NEW HYALURONIC ACID DERIVATIVES AS INNOVATIVE FILLERS CD44, MMP1, HAAO AKR1B1 3346/4885PTPN1 4618/4885APP 4602/4885
US-12018307-B2 Process for producing a glucuronide and genetically modified microorganisms useful in this process GUSB, UGT1A4, UGT1A6 AKR1B1 284/4885PTPN1 2895/4885APP 2773/4885
US-11812742-B2 Biocidal solar cell XPA, CRY1, MAVS AKR1B1 3112/4885PTPN1 2245/4885APP 446/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.