Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 2/20 | 0.38 |
| ▸ | IKBKB | O14920 | 1/20 | 0.35 |
| ▸ | ALOX5 | P09917 | 5/20 | 0.35 |
| ▸ | LDHA | P00338 | 3/20 | 0.35 |
| ▸ | LDHB | P07195 | 3/20 | 0.35 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.35 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.35 |
| ▸ | HMGCR | P04035 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAOA | P21397 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.32 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.32 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.32 |
| ▸ | PRKCI | P41743 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13788027 | 0.95 | DHFR (0.36) | DHFRIKBKBALOX5LDHALDHB | |
| SCHEMBL12339812 | 0.89 | TYR (0.40) | ALOX5GABRA1GABRB2ALOX15MAOA | |
| SCHEMBL12339808 | 0.85 | DHFR (0.38) | DHFRGABRA1GABRB2ALOX15MAOA | |
| SCHEMBL19972031 | 0.77 | DHFR (0.37) | DHFRALOX5LDHALDHBGABRA1 | |
| SCHEMBL12339816 | 0.76 | GABRA1 (0.41) | IKBKBGABRA1GABRB2ALOX15 | |
| SCHEMBL29662311 | 0.76 | ALDH1A1 (0.45) | ALOX15 | |
| SCHEMBL899192 | 0.76 | ALDH1A1 (0.45) | ALOX15 | |
| SCHEMBL3797886 | 0.73 | NOS2 (0.38) | IKBKBHMGCR | |
| SCHEMBL11374001 | 0.73 | HMGCR (0.42) | ALOX5LDHALDHBHMGCRMAOA | |
| SCHEMBL1987359 | 0.72 | AMY1A (0.57) | DHFRALOX5HMGCRMAOAPRKCI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8269358-B2 | Bis(aminophenol) derivative, process for producing same, polyamide resin, positive photosensitive resin composition, protective film, interlayer dielectric film, semiconductor device, and display element | SUMITOMO BAKELITE COMPANY LIMITED (JP) | 2012-09-18 | — | — | US | disclosed |
| US-20100044888-A1 | BIS(AMINOPHENOL) DERIVATIVE, PROCESS FOR PRODUCING SAME, POLYAMIDE RESIN, POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PROTECTIVE FILM, INTERLAYER DIELECTRIC FILM, SEMICONDUCTOR DEVICE, AND DISPLAY ELEMENT | SUMITOMO BAKELITE COMPANY LIMITED (JP) | 2010-02-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100044888-A1 | BIS(AMINOPHENOL) DERIVATIVE, PROCESS FOR PRODUCING SAME, POLYAMIDE RESIN, POSITIVE PHOTOSENSITIVE RESIN COMPOSITION, PROTECTIVE FILM, INTERLAYER DIELECTRIC FILM, SEMICONDUCTOR DEVICE, AND DISPLAY ELEMENT | RARA, AASDHPPT, GABRP | DHFR 3714/4885IKBKB 3713/4885ALOX5 2436/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.