SCHEMBL12353909

SCHEMBL12353909

CC(C)(C)c1cccc(-n2c3ccccc3c3ccccc32)c1

nearest known ligand 0.53

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 1/20 0.53
▸ ATM Q13315 1/20 0.53
▸ L3MBTL1 Q9Y468 1/20 0.53
▸ NOTUM Q6P988 1/20 0.47
▸ PPARG P37231 4/20 0.39
▸ PPARA Q07869 1/20 0.39
▸ KIF11 P52732 4/20 0.39
▸ OPRD1 P41143 2/20 0.38
▸ GPR3 P46089 1/20 0.38
▸ PLA2G10 O15496 1/20 0.38
▸ HDAC4 P56524 1/20 0.37
▸ HDAC2 Q92769 1/20 0.37
▸ HDAC8 Q9BY41 1/20 0.37
▸ POLB P06746 1/20 0.36
▸ ESRRA P11474 1/20 0.36
▸ PGR P06401 1/20 0.35
▸ RORA P35398 1/20 0.35
▸ RORC P51449 1/20 0.35
▸ RORB Q92753 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16940886 0.95 KDM4E (0.48) KDM4EATML3MBTL1NOTUMPPARG
SCHEMBL25708821 0.95 KDM4E (0.48) KDM4EATML3MBTL1NOTUMPPARG
SCHEMBL25708814 0.94 KDM4E (0.47) KDM4EATML3MBTL1NOTUMPPARG
SCHEMBL17228098 0.92 KDM4E (0.46) KDM4EATML3MBTL1NOTUMPPARG
SCHEMBL12000707 0.90 KDM4E (0.47) KDM4EATML3MBTL1NOTUMPPARG
SCHEMBL13232835 0.90 L3MBTL1 (0.50) KDM4EATML3MBTL1NOTUMPPARG
SCHEMBL8739873 0.90 L3MBTL1 (0.50) KDM4EATML3MBTL1NOTUMPPARG
SCHEMBL8739871 0.90 L3MBTL1 (0.50) KDM4EATML3MBTL1NOTUMPPARG
SCHEMBL27119985 0.89 KDM4E (0.43) KDM4EATML3MBTL1NOTUMPPARG
SCHEMBL13132834 0.88 L3MBTL1 (0.48) KDM4EATML3MBTL1NOTUMPPARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 157 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same LG CHEM, LTD. (KR) 2024-07-16 — — US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 — — US disclosed
US-12035618-B2 Electroluminescent devices UNIVERSAL DISPLAY CORPORATION (US) 2024-07-09 — — US disclosed
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2024-07-04 — — US disclosed
US-11917900-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 — — US disclosed
US-11917900-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-02-27 — — US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 — — US disclosed
US-11864458-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2024-01-02 — — US disclosed
US-20230389421-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2023-11-30 — — US disclosed
US-11827615-B2 Nitrogen-containing compound, electronic element and electronic device SHAANXI LIGHTE OPTOELECTRONICS MATERIAL CO., LTD. (CN) 2023-11-28 — — US disclosed
US-20160372679-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP. (TW) 2016-12-22 — — US disclosed
US-20160336518-A1 ORGANIC LIGHT-EMITTING DEVICE LG CHEM, LTD. (KR) 2016-11-17 — — US disclosed
US-20160233431-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME LG CHEM, LTD. (KR) 2016-08-11 — — US disclosed
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF LUMINESCENCE TECHNOLOGY CORP. 2016-07-21 — — US disclosed
US-9386657-B2 Organic Electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2016-07-05 — — US disclosed
US-9190619-B2 Compound for organic electroluminescence device LUMINESCENCE TECHNOLOGY CORP (TW) 2015-11-17 — — US disclosed
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE LUMINESCENCE TECHNOLOGY CORP (TW) 2015-07-30 — — US disclosed
US-20140124762-A1 ORGANIC CONDUCTIVE MATERIALS AND DEVICES MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) 2014-05-08 — — US disclosed
US-20130241400-A1 SECONDARY HOLE TRANSPORTING LAYER WITH TRICARBAZOLE COMPOUNDS UNIVERSAL DISPLAY CORPORATION (US) 2013-09-19 — — US disclosed
US-7993763-B2 Emissive core of an iridium atom and ligands coordinated to the metal atom; a host group with two rings or a heteroaryl group with two rings and a terminal alkyl group, a heteroalkyl group, an aryl group, or a heteroaryl group; organic phototransistors, organic photovoltaic cells UNIVERSAL DISPLAY CORPORATION (US) 2011-08-09 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (11 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12035618-B2 Electroluminescent devices ELAVL1, ELAVL3, JUND KDM4E 3586/4885ATM 4463/4885L3MBTL1 440/4885
US-12041848-B2 Heterocyclic compound and organic light emitting element comprising same CRY1, CRY2, NR2E3 KDM4E 1039/4885ATM 2081/4885L3MBTL1 622/4885
US-20160372679-A1 COMPOUNDS FOR ORGANIC ELECTROLUMINESCENCE DEVICE CCNE2, CYP3A4, CCNE1 KDM4E 1289/4885ATM 2012/4885L3MBTL1 114/4885
US-20130241400-A1 SECONDARY HOLE TRANSPORTING LAYER WITH TRICARBAZOLE COMPOUNDS SLC25A1, ABCG2, SLC43A1 KDM4E 3261/4885ATM 3366/4885L3MBTL1 466/4885
US-11864458-B2 Organic electroluminescent materials and devices RAP1A, L1CAM, SOD1 KDM4E 1807/4885ATM 2489/4885L3MBTL1 1195/4885
US-11827615-B2 Nitrogen-containing compound, electronic element and electronic device NOS1, PRMT1, MNS1 KDM4E 1469/4885ATM 694/4885L3MBTL1 2139/4885
US-20240224783-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG KDM4E 3179/4885ATM 4355/4885L3MBTL1 822/4885
US-20150214492-A1 COMPOUND FOR ORGANIC ELECTROLUMINESCENCE DEVICE SLCO4C1, LEF1, SLCO2B1 KDM4E 2458/4885ATM 3958/4885L3MBTL1 1111/4885
US-20160211456-A1 PHENANTHRO[9,10-b]TETRAPHENYLENE DERIVATIVE AND USE THEREOF POP1, TERB1, AP2B1 KDM4E 2546/4885ATM 3949/4885L3MBTL1 334/4885
US-11917900-B2 Organic electroluminescent materials and devices OTC, OSBP, OCIAD2 KDM4E 3522/4885ATM 4067/4885L3MBTL1 1605/4885
US-20160233431-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING ELEMENT USING SAME CRY1, CRY2, NR2E3 KDM4E 1127/4885ATM 2709/4885L3MBTL1 854/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

Send feedback