SCHEMBL1238985

SCHEMBL1238985

O=C([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[Na+]

nearest known ligand 0.56

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 1/20 0.56
CA2 known ✓ P00918 15/20 0.38
CA1 known ✓ P00915 14/20 0.38
MMP1 P03956 2/20 0.38
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
MMP8 P22894 2/20 0.38
MMP13 P45452 2/20 0.38
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.31
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28669167 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL29841771 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL4871654 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL2368073 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL3366661 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL28403558 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL28411715 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL151831 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL5067306 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL28659605 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1253 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250353752-A1 PREPARATION METHOD FOR SILICON DIOXIDE AEROGEL AND SILICON DIOXIDE AEROGEL HUNAN ALFY NEW MAT CO LTD (CN) 2025-11-20 US claimed
CN-120040542-A Formula capable of collecting low-pI protein charge variant component and application thereof 上海奥浦迈生物科技股份有限公司 2025-05-27 CN claimed
CN-115494247-B Thrombin time quality control product and preparation method and application thereof 上海太阳生物技术有限公司 2025-05-13 CN claimed
CN-115436647-B Fibrinogen quality control product and preparation method and application thereof 上海太阳生物技术有限公司 2025-05-13 CN claimed
CN-119944237-A Lithium battery diaphragm with high heat resistance and low water absorption and preparation method thereof 天津东皋膜技术有限公司 2025-05-06 CN claimed
CN-116282300-B Photothermal conversion composite material suitable for purifying oily wastewater and organic wastewater and preparation method thereof 南京理工大学 2025-05-02 CN claimed
CN-119224093-B Preparation method and application of molecular crystal thin film organic field effect transistor biosensor based on ultrathin sensing layer 天津大学 2025-04-22 CN claimed
CN-119639441-A Seawater-based Gao Wengua-resistant glue fracturing fluid and preparation method thereof 中海油能源发展股份有限公司工程技术分公司 2025-03-18 CN claimed
CN-116139595-B PTFE catalytic filter material and preparation method thereof 中国恩菲工程技术有限公司 2025-03-14 CN claimed
CN-119612707-A Method for degrading organic matters by electrochemical lithium extraction coupling electrooxidation of water produced by oil and gas field 中国石油大学(北京) 2025-03-14 CN claimed
CN-100999560-A Fluorine elastomer containing high fluorine content and preparation process thereof ZHONGHAO CHENGGUANG CHEMICAL R (CN) 2007-07-18 CN claimed
CN-1304522-C Fracturing working fluid for reservoir containing tufaceous matter DAQING OILFIELD CO LTD (CN) 2007-03-14 CN claimed
CN-1817913-A Production of hydrotalcite-modified polyvinylidene fluoride-based gel electrolyte UNIV ZHEJIANG (CN) 2006-08-16 CN claimed
CN-1664048-A Fracturing working fluid for reservoir containing tufaceous matter DAQING OILFIELD CO LTD (CN) 2005-09-07 CN claimed
CN-1202232-C Glass cleaning agent composite for electronic industry UNIV SHANDONG (CN) 2005-05-18 CN claimed
CN-1174084-C Liquid fuel and its preparing method 吴一平 2004-11-03 CN claimed
CN-1458249-A Liquid fuel and its preparing method WU YIPING (CN) 2003-11-26 CN claimed
EP-0931798-B1 Process for preparing modified PTFE SOLVAY SOLEXIS SPA (IT) 2003-05-14 EP claimed
US-6262209-B1 SUSPENSION POLYMERIZING PERFLUOROALKYLVINYLETHER AND/OR PERFLUORODIOXOLE AUSIMONT S.P.A. (IT) 2001-07-17 US claimed
EP-0931798-A1 Process for preparing modified PTFE Ausimont S.p.A. (IT) 1999-07-28 EP claimed