SCHEMBL5067306

SCHEMBL5067306

O=C([O-])C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)C(F)(F)F.[Na+]

nearest known ligand 0.56

Known targets — ChEMBL curated mechanism

ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
THRB known ✓ P10828 1/20 0.56
CA2 known ✓ P00918 15/20 0.38
CA1 known ✓ P00915 14/20 0.38
MMP1 P03956 2/20 0.38
MMP2 P08253 2/20 0.38
MMP9 P14780 2/20 0.38
MMP8 P22894 2/20 0.38
MMP13 P45452 2/20 0.38
LMNA P02545 1/20 0.33
GAA P10253 1/20 0.31
F2 P00734 1/20 0.30
PRSS1 P07477 1/20 0.30
PRSS2 P07478 1/20 0.30
PRSS3 P35030 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28669167 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL1238985 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL29841771 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL4871654 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL2368073 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL3366661 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL28403558 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL28411715 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL151831 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2
SCHEMBL28659605 1.00 THRB (0.56) THRBCA2CA1MMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107989600-B Water-based trace chemical tracer and method for measuring connectivity between water injection wells 捷贝通石油技术集团股份有限公司 2023-09-12 CN claimed
CN-113653486-A Slow-release type long-acting tracer and preparation method thereof 捷贝通石油技术集团股份有限公司 2021-11-16 CN claimed
WO-2026102095-A1 METHODS FOR DETECTING PER- OR POLY-FLUOROALKYL SUBSTANCES WITH FLUOROPHORES UNIVERSITY OF UTAH RESEARCH FOUNDATION (US) 2026-05-15 WO disclosed
US-12319594-B2 Composition and method for capture and degradation of PFAS BATTELLE MEMORIAL INSTITUTE (US) 2025-06-03 US disclosed
US-11991912-B2 Display panel and manufacturing method thereof WUHAN CHINA STAR OPTOELECTRONICS SEMICONDUCTOR DISPLAY TECHNOLOGY CO., LTD. (CN) 2024-05-21 US disclosed
US-11891313-B2 Fluidic impedance platform for in-situ detection and quantification of PFAS in groundwater BATTELLE MEMORIAL INSTITUTE (US) 2024-02-06 US disclosed
CN-107989600-B Water-based trace chemical tracer and method for measuring connectivity between water injection wells 捷贝通石油技术集团股份有限公司 2023-09-12 CN disclosed
WO-2023122143-A1 METHODS AND COMPOSITIONS FOR PFAS DEFLUORINATION DETECTION GINKGO BIOWORKS, INC. (US) 2023-06-29 WO disclosed
US-20230089418-A1 COMPOSITION AND METHOD FOR CAPTURE AND DEGRADATION OF PFAS BATTELLE MEMORIAL INSTITUTE (US) 2023-03-23 US disclosed
US-11518689-B2 Composition and method for capture and degradation of PFAS BATTELLE MEMORIAL INSTITUTE (US) 2022-12-06 US disclosed
CN-111333501-B Preparation method of fluorine-containing carboxylic acid 中蓝晨光化工研究设计院有限公司 2022-11-04 CN disclosed
CN-111725420-B Display panel and preparation method thereof 武汉华星光电半导体显示技术有限公司 2021-08-03 CN disclosed
US-20200369536-A1 COMPOSITION AND METHOD FOR CAPTURE AND DEGRADATION OF PFAS BATTELLE MEMORIAL INSTITUTE (US) 2020-11-26 US disclosed
CN-111725420-A Display panel and preparation method thereof 武汉华星光电半导体显示技术有限公司 2020-09-29 CN disclosed
US-7351342-B2 Method for recovering fluorine-containing emulsifier ASAHI GLASS COMPANY, LIMITED (JP) 2008-04-01 US disclosed
EP-1514848-B1 PROCESS FOR THE RECOVERY OF FLUORINE-CONTAINING EMULSIFIERS SASAKURA ENG CO LTD (JP) 2006-04-05 EP disclosed
US-20050150833-A1 Method for recovering fluorine-containing emulsifier ASAHI GLASS COMPANY LIMITED (JP) 2005-07-14 US disclosed
EP-1514848-A1 PROCESS FOR THE RECOVERY OF FLUORINE-CONTAINING EMULSIFIERS Sasakura Engineering Co. Ltd. (JP) 2005-03-16 EP disclosed
US-20030098282-A1 Method for adsorbing and recovering fluorine-containing emulsifier ASAHI GLASS COMPANY, LIMITED (JP) 2003-05-29 US disclosed
EP-1314700-A1 Method for absorbing and recovering fluorine-containing emulsifier ASAHI GLASS COMPANY LTD. (JP) 2003-05-28 EP disclosed