Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acrylic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30326885 | 0.95 | — | — | |
| Acrylic Acid SCHEMBL31339230 | 0.90 | LMNA (0.32) | — | |
| Acrylamide SCHEMBL29620829 | 0.89 | ALDH1A1 (0.34) | — | |
| Acrylic Acid SCHEMBL4760578 | 0.87 | — | — | |
| SCHEMBL29554649 | 0.81 | TSHR (0.49) | — | |
| SCHEMBL94258 | 0.78 | — | — | |
| SCHEMBL29642706 | 0.76 | — | — | |
| Ammonia Solution, Strong SCHEMBL2802434 | 0.76 | — | — | |
| Acrylic Acid SCHEMBL149402 | 0.72 | TSHR (0.40) | — | |
| Acrylamide SCHEMBL30508942 | 0.72 | ALDH1A1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10945942-B2 | Starting material for cosmetics | SHISEIDO COMPANY, LTD. (JP) | 2021-03-16 | — | — | US | disclosed |
| US-20170239165-A1 | STARTING MATERIAL FOR COSMETICS | SHISEIDO COMPANY, LTD. (JP) | 2017-08-24 | — | — | US | disclosed |
| US-8293222-B2 | Silicone-modified wax-containing composition and cosmetic preparation containing the composition | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2012-10-23 | — | — | US | disclosed |
| EP-2347794-A2 | Silicone-modified wax-containing composition and cosmetic preparation containing the composition | Shin-Etsu Chemical Co., Ltd. (JP) | 2011-07-27 | — | — | EP | disclosed |
| US-20110028571-A1 | SILICONE-MODIFIED WAX-CONTAINING COMPOSITION AND COSMETIC PREPARATION CONTAINING THE COMPOSITION | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 2011-02-03 | — | — | US | disclosed |