SCHEMBL12419185

SCHEMBL12419185

CCC(C)(C)C(=O)OCc1cccc2c(Br)cccc12

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ RIPK1 Q13546 6/20 0.45
▸ MMP1 P03956 1/20 0.36
▸ MMP2 P08253 1/20 0.36
▸ MMP9 P14780 1/20 0.36
▸ MMP12 P39900 1/20 0.36
▸ KMT2A Q03164 4/20 0.36
▸ MEN1 O00255 3/20 0.36
▸ LMNA P02545 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35
▸ MAPT P10636 2/20 0.35
▸ RAB9A P51151 2/20 0.35
▸ POLB P06746 1/20 0.35
▸ PKM P14618 1/20 0.35
▸ ALDH1A1 P00352 2/20 0.33
▸ PRNP P04156 1/20 0.33
▸ KDM4E B2RXH2 1/20 0.33
▸ GLA P06280 1/20 0.33
▸ NPC1 O15118 1/20 0.33
▸ AHR P35869 1/20 0.33
▸ ATM Q13315 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12419176 0.84 ALDH1A1 (0.41) RIPK1LMNAL3MBTL1MAPTPOLB
SCHEMBL8738362 0.84 CDC25B (0.39) RIPK1ALDH1A1GABRA1GABRB2
SCHEMBL12419175 0.83 LMNA (0.41) RIPK1MMP1MMP2MMP9MMP12
SCHEMBL12419171 0.83 ATM (0.49) KMT2AMEN1L3MBTL1ALDH1A1KDM4E
SCHEMBL8737838 0.79 RIPK1 (0.40) RIPK1L3MBTL1RAB9AKDM4ENPC1
SCHEMBL13292523 0.77 MTNR1A (0.42) RIPK1KMT2AMEN1ALDH1A1KDM4E
SCHEMBL29324088 0.76 IDH1 (0.42) KMT2AMEN1ALDH1A1KDM4EGLA
SCHEMBL24859837 0.75 MMP1 (0.34) RIPK1MMP1MMP2MMP9MMP12
SCHEMBL17552774 0.74 RIPK1 (0.57) RIPK1MMP1MMP2MMP9MMP12
SCHEMBL17552770 0.74 RIPK1 (0.56) RIPK1MMP1MMP2MMP9MMP12

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180180998-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-06-28 — — US disclosed
US-20180039175-A1 NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2018-02-08 — — US disclosed
US-9740098-B2 Chemically amplified negative resist composition using novel onium salt and resist pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-08-22 — — US disclosed
US-9604921-B2 Sulfonium salt, resist composition and resist pattern forming process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2017-03-28 — — US disclosed
US-20160299428-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION USING NOVEL ONIUM SALT AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-10-13 — — US disclosed
US-9436083-B2 Chemically-amplified negative resist composition and resist patterning process using the same SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-09-06 — — US disclosed
US-9329476-B2 Chemically amplified negative resist composition and patterning process SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-05-03 — — US disclosed
US-20160090355-A1 SULFONIUM SALT, RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2016-03-31 — — US disclosed
US-20150268556-A1 CHEMICALLY-AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERNING PROCESS USING THE SAME SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-09-24 — — US disclosed
US-20150198877-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2015-07-16 — — US disclosed
US-20110171579-A1 NEGATIVE RESIST COMPOSITION AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2011-07-14 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180180998-A1 CHEMICALLY AMPLIFIED NEGATIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS SLC11A2, POLR2B, POLI RIPK1 1282/4885MMP1 4441/4885MMP2 4516/4885
US-20160090355-A1 SULFONIUM SALT, RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS ETV6, ETV1, EIF2B3 RIPK1 1653/4885MMP1 4106/4885MMP2 3989/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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