Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.48 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325898 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL5706178 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL3192403 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL9780310 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL133846 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL3063106 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL7191365 | 0.98 | KMT2A (0.52) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| Potassium Ion SCHEMBL6902487 | 0.97 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL8820326 | 0.92 | KMT2A (0.48) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL31314548 | 0.92 | KMT2A (0.48) | KMT2ASMN1; SMN2CA2NR1I2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 205 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000078676-A1 | USE OF ACTIVATED PHYLLOSILICATES IN NON-AQUEOUS LIQUID DETERGENTS | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2000-12-28 | — | — | WO | claimed |
| US-4539130-A | SULFONATE AND CARBOXYLIC ACID ESTERS, ANHYDRIDES AND IMIDE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1985-09-03 | — | — | US | claimed |
| EP-2536815-B1 | USE OF LIPOSOMES FOR THE TREATMENT OF TEXTILE MATERIALS | LIPOTEC SA (ES) | 2018-07-11 | — | — | EP | disclosed |
| US-9717659-B2 | Liposomes for the treatment of textile materials | LIPOTEC, S.A. (ES) | 2017-08-01 | — | — | US | disclosed |
| EP-3114933-A1 | STAR BLOCK COMB POLYMERS AS BIOACTIVE CARRIER MATRIX FOR THE DRUG ELUTING SEMI-PERMANENT COATING OF SURFACES | Henkel AG & Co. KGaA (DE) | 2017-01-11 | — | — | EP | disclosed |
| US-9353361-B2 | Alpha-amylase variants stabilized against dimerization and/or multimerization, method for the production thereof, and detergents and cleansers containing these alpha-amylase variants | BASF SE (DE) | 2016-05-31 | — | — | US | disclosed |
| EP-1794292-B1 | ALPHA-AMYLASE VARIANTS STABILIZED AGAINST DIMERIZATION AND/OR MULTIMERIZATION, METHOD FOR THE PRODUCTION THEREOF, AND DETERGENTS AND CLEANSERS CONTAINING THESE ALPHA-AMYLASE VARIANTS | BASF SE (DE) | 2015-12-30 | — | — | EP | disclosed |
| US-20150118733-A1 | Alpha-Amylase Variants Stabilized Against Dimerization and/or Multimerization, Method for the Production Thereof, and Detergents and Cleansers Containing these Alpha-Amylase Variants | BASF SE (DE) | 2015-04-30 | — | — | US | disclosed |
| US-8785365-B2 | Alpha-amylase variants stabilized against dimerization and/or multimerization, method for the production thereof, and detergents and cleansers containing these alpha-amylase variants | BASF SE (DE) | 2014-07-22 | — | — | US | disclosed |
| EP-1463810-B1 | Glycosyl hydrolase | BRAIN BIOTECHNOLOGY RES & INFORMATION NETWORK AG (DE) | 2014-05-14 | — | — | EP | disclosed |
| US-8580549-B2 | Esterases for separating plastics | HENKEL KGAA (DE) | 2013-11-12 | — | — | US | disclosed |
| EP-0269168-A2 | Softening detergent compositions containing cellulase | THE PROCTER & GAMBLE COMPANY (US) | 1988-06-01 | — | — | EP | disclosed |
| EP-0150532-B1 | PEROXYGEN BLEACH ACTIVATORS AND BLEACHING COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 1988-05-04 | — | — | EP | disclosed |
| EP-0242918-A1 | Softening and bleaching detergent compositions containing amide softening agent | THE PROCTER & GAMBLE COMPANY (US) | 1987-10-28 | — | — | EP | disclosed |
| EP-0242919-A1 | Softening detergent compositions containing amide softening agent | THE PROCTER & GAMBLE COMPANY (US) | 1987-10-28 | — | — | EP | disclosed |
| US-4588532-A | Preparation of para-acyloxybenzene sulfonates | RHONE-POULENC CHIMIE DE BASE (FR) | 1986-05-13 | — | — | US | disclosed |
| US-4539130-A | SULFONATE AND CARBOXYLIC ACID ESTERS, ANHYDRIDES AND IMIDE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1985-09-03 | — | — | US | disclosed |
| EP-0150532-A1 | Peroxygen bleach activators and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 1985-08-07 | — | — | EP | disclosed |
| US-4486327-A | FOR PEROXYGEN COMPOUNDS | THE PROCTER & GAMBLE COMPANY (US) | 1984-12-04 | — | — | US | disclosed |
| US-4483778-A | Peroxygen bleach activators and bleaching compositions | THE PROCTER & GAMBLE COMPANY (US) | 1984-11-20 | — | — | US | disclosed |