Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 known ✓ | P00918 | 3/20 | 0.48 |
| ▸ | PTGS2 known ✓ | P35354 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | BCL9 | O00512 | 1/20 | 0.46 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.46 |
| ▸ | STS | P08842 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6325898 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL5706178 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL3192403 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL1249882 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL9780310 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL3063106 | 1.00 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL7191365 | 0.98 | KMT2A (0.52) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| Potassium Ion SCHEMBL6902487 | 0.97 | KMT2A (0.54) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL8820326 | 0.92 | KMT2A (0.48) | KMT2ASMN1; SMN2CA2NR1I2NPC1 | |
| SCHEMBL31314548 | 0.92 | KMT2A (0.48) | KMT2ASMN1; SMN2CA2NR1I2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 454 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107920973-B | Surface modification composition | 株式会社LG生活健康 | 2021-05-07 | — | — | CN | claimed |
| CN-111387189-A | Disinfectant composition | 成都汉凰生物技术有限公司 | 2020-07-10 | — | — | CN | claimed |
| CN-110774397-A | Production system and production method of bleached lignocellulose | 上海同化新材料科技有限公司 | 2020-02-11 | — | — | CN | claimed |
| EP-3342395-A2 | COMPOSITION FOR SURFACE MODIFICATION | LG Household & Health Care Ltd. (KR) | 2018-07-04 | — | — | EP | claimed |
| US-20090176681-A1 | Bleach composition and bleaching detergent composition | KANEDA HIDEYUKI | 2009-07-09 | — | — | US | claimed |
| US-7524804-B2 | Bleach composition and bleaching detergent composition | CIBA SPECIALTY CHEMICALS CORP. (US) | 2009-04-28 | — | — | US | claimed |
| EP-1621605-B1 | BLEACH COMPOSITION AND BLEACHING DETERGENT COMPOSITION | CIBA HOLDING INC (CH) | 2008-06-25 | — | — | EP | claimed |
| WO-2007131529-A1 | TEXTILE TREATMENT AGENT | HENKEL KOMMANDITGESELLSCHAFT AUF AKTIEN (DE) | 2007-11-22 | — | — | WO | claimed |
| US-20060293204-A1 | Bleach composition and bleaching detergent composition | CIBA SPECIALTY CHEMICALS CORP. | 2006-12-28 | — | — | US | claimed |
| EP-1621605-A1 | BLEACH COMPOSITION AND BLEACHING DETERGENT COMPOSITION | Ciba Specialty Chemicals Holding Inc. (CH) | 2006-02-01 | — | — | EP | claimed |
| EP-1286960-B1 | IMPROVED ISOLATION OF PHENYL ESTER SALTS FROM MIXTURES COMPRISING SULFOLANE | EASTMAN CHEM CO (US) | 2004-08-18 | — | — | EP | claimed |
| EP-1286960-A2 | IMPROVED ISOLATION OF PHENYL ESTER SALTS FROM MIXTURES COMPRISING SULFOLANE | EASTMAN CHEMICAL COMPANY (US) | 2003-03-05 | — | — | EP | claimed |
| EP-1286959-A2 | EXTRACTIVE SOLUTION CRYSTALLIZATION OF CHEMICAL COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2003-03-05 | — | — | EP | claimed |
| US-6500973-B2 | SOLVENT EXTRACTION OF PHENYL ESTER | EASTMAN CHEMICAL COMPANY | 2002-12-31 | — | — | US | claimed |
| US-6498124-B2 | ADJUSTING THE TEMPERATURE OF A FIRST MIXTURE COMPRISING A PHENYL ESTER SALT AND SULFOLANE TO FORM SECOND MIXTURE; SEPARATING THE SOLID PHENYL ESTER SALT FROM THE SECOND MIXTURE WHILE MAINTAINING THE TEMPERATURE OF THE MIXTURE | EASTMAN CHEMICAL COMPANY | 2002-12-24 | — | — | US | claimed |
| US-20020040151-A1 | Isolation of phenyl ester salts from mixtures comprising sulfolane | EASTMAN CHEMICAL COMPANY | 2002-04-04 | — | — | US | claimed |
| US-20020035284-A1 | Extractive solution crystallization of chemical compounds | EASTMAN CHEMICAL COMPANY | 2002-03-21 | — | — | US | claimed |
| WO-2001094302-A2 | EXTRACTIVE SOLUTION CRYSTALLIZATION OF CHEMICAL COMPOUNDS | EASTMAN CHEMICAL COMPANY (US) | 2001-12-13 | — | — | WO | claimed |
| WO-2001094303-A2 | IMPROVED ISOLATION OF PHENYL ESTER SALTS FROM MIXTURES COMPRISING SULFOLANE | EASTMAN CHEMICAL COMPANY (US) | 2001-12-13 | — | — | WO | claimed |
| US-4539130-A | SULFONATE AND CARBOXYLIC ACID ESTERS, ANHYDRIDES AND IMIDE DERIVATIVES | THE PROCTER & GAMBLE COMPANY (US) | 1985-09-03 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020040151-A1 | Isolation of phenyl ester salts from mixtures comprising sulfolane | SULT1E1, SULT1A1, STS | CA2 140/4885PTGS2 1436/4885KMT2A 2759/4885 |
| US-20020035284-A1 | Extractive solution crystallization of chemical compounds | HPSE, HAAO, APEH | CA2 362/4885PTGS2 4491/4885KMT2A 4404/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.