Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.34 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.33 |
| ▸ | ITGAV | P06756 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12590064 | 0.83 | HTT (0.37) | HTTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL24708055 | 0.81 | MTNR1A (0.38) | HTTALDH1A1FOLH1MEN1KMT2A | |
| SCHEMBL17831028 | 0.79 | HTT (0.34) | HTTALDH1A1SMN1; SMN2KDM4ELMNA | |
| SCHEMBL18081560 | 0.79 | ALDH1A1 (0.37) | HTTALDH1A1FOLH1MEN1KMT2A | |
| SCHEMBL14984422 | 0.78 | HDAC3 (0.40) | HTTALDH1A1FOLH1MEN1KMT2A | |
| SCHEMBL12799292 | 0.78 | LMNA (0.46) | HTTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL17831027 | 0.78 | LMNA (0.46) | HTTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL13609856 | 0.78 | LMNA (0.46) | HTTALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL16602341 | 0.77 | ITGB3 (0.46) | HTTALDH1A1FOLH1KMT2AITGB3 | |
| SCHEMBL14984432 | 0.77 | ALDH1A1 (0.40) | HTTALDH1A1FOLH1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20160166717-A1 | RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2016-06-16 | — | — | US | disclosed |
| US-20160166717-A1 | RADIOLABELLING METHOD | GE HEALTHCARE LIMITED (GB) | 2016-06-16 | — | — | US | disclosed |
| US-7902332-B2 | Reacting thiol-reactive terminus of linker with a polypeptide and fluorine-substituted aldehyde | GENERAL ELECTRIC COMPANY (US) | 2011-03-08 | — | — | US | disclosed |
| US-20090274623-A1 | IN VIVO IMAGING AGENTS FOR MET RECEPTOR TYROSINE KINASE | GENERAL ELECTRIC COMPANY (US) | 2009-11-05 | — | — | US | disclosed |
| US-20080139787-A1 | Fluorine-labeled compounds | GENERAL ELECTRIC COMPANY | 2008-06-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080139787-A1 | Fluorine-labeled compounds | PFAS, DHFR, PAICS | HTT 1849/4885ALDH1A1 226/4885FOLH1 7/4885 |
| US-20090274623-A1 | IN VIVO IMAGING AGENTS FOR MET RECEPTOR TYROSINE KINASE | MET, HGFAC, HGF | HTT 462/4885ALDH1A1 3475/4885FOLH1 111/4885 |
| US-20160166717-A1 | RADIOLABELLING METHOD | QPCT, ARF5, PAICS | HTT 2583/4885ALDH1A1 2454/4885FOLH1 116/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.