SCHEMBL12848813

SCHEMBL12848813

Cc1oc(C(C)C)cc1C(C)C

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
LMNA P02545 3/20 0.34
TRPA1 O75762 1/20 0.34
CHRM1 P11229 1/20 0.34
SLC6A2 P23975 1/20 0.34
ADRA1A P35348 1/20 0.34
HTR2B P41595 1/20 0.34
GPR55 Q9Y2T6 1/20 0.34
ALOX5 P09917 1/20 0.33
GABRA1 P14867 5/20 0.32
GABRB1 P18505 3/20 0.32
GABRB2 P47870 2/20 0.32
NPC1 O15118 1/20 0.31
MGAM O43451 1/20 0.31
GAA P10253 1/20 0.31
SI P14410 1/20 0.31
PTPN1 P18031 1/20 0.31
ACHE P22303 1/20 0.31
RAB9A P51151 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4298346 0.81 ALOX5 (0.48) CA1CA2LMNATRPA1CHRM1
SCHEMBL949953 0.79 SLC6A4 (0.32) LMNATRPA1CHRM1SLC6A2ADRA1A
SCHEMBL8230453 0.78 TAS1R3 (0.32) LMNATRPA1GPR55NPC1MGAM
SCHEMBL21479471 0.77 GPR55 (0.32) CA1CA2LMNATRPA1CHRM1
SCHEMBL13076102 0.76
SCHEMBL12795929 0.76 CA1 (0.33) CA1CA2GABRA1GABRB1GABRB2
SCHEMBL5164773 0.74
SCHEMBL12914095 0.74 POLB (0.36) LMNAGPR55GABRA1GABRB1GAA
SCHEMBL8224149 0.74 L3MBTL1 (0.44) LMNANPC1GAARAB9AMAPT
SCHEMBL21479468 0.72 LMNA (0.33) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11634445-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-04-25 US disclosed
US-20200369699-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2020-11-26 US disclosed
US-20190315788-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2019-10-17 US disclosed
US-20110052643-A1 COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES SYNTA PHARMACEUTICALS CORP. (US) 2011-03-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200369699-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, EPCAM, SOD1 CA1 1023/4885CA2 1460/4885LMNA 731/4885
US-20110052643-A1 COMPOUNDS FOR INFLAMMATION AND IMMUNE-RELATED USES TSLP, NFATC1, IL5 CA1 3904/4885CA2 2262/4885LMNA 4871/4885
US-20190315788-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES L1CAM, LEF1, ZYX CA1 1317/4885CA2 2650/4885LMNA 185/4885
US-11634445-B2 Organic electroluminescent materials and devices L1CAM, EPCAM, SOD1 CA1 1023/4885CA2 1460/4885LMNA 731/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.