Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.44 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.44 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 2/20 | 0.44 |
| ▸ | RELA | Q04206 | 3/20 | 0.40 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHAT | P28329 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14528541 | 0.90 | RELA (0.38) | MAOBNFE2L2CYP19A1MAOARELA | |
| SCHEMBL14528356 | 0.85 | RELA (0.35) | MAOBNFE2L2CYP19A1MAOARELA | |
| SCHEMBL12880577 | 0.84 | CES2 (0.48) | TRPA1CES2CES1LMNA | |
| SCHEMBL28808628 | 0.83 | NFE2L2 (0.48) | MAOBNFE2L2CYP19A1MAOARELA | |
| SCHEMBL1903577 | 0.82 | ALDH1A1 (0.54) | TRPA1CES2CES1LMNA | |
| SCHEMBL67123 | 0.82 | CES2 (0.50) | TRPA1CES2CES1LMNA | |
| SCHEMBL11447690 | 0.81 | MAOB (0.50) | MAOBNFE2L2CYP19A1MAOARELA | |
| SCHEMBL4438717 | 0.78 | MAOB (0.52) | MAOBNFE2L2CYP19A1MAOARELA | |
| SCHEMBL4986109 | 0.78 | MAOB (0.52) | MAOBNFE2L2CYP19A1MAOARELA | |
| SCHEMBL12880591 | 0.77 | CHRNB2 (0.50) | MAOATRPA1CES2CES1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7884175-B2 | polymerizing one or more monomers containing dihalogen containing substituted biaryls, via a base-induced dehydrohalogenation | MERCK PATENT GMBH (DE) | 2011-02-08 | — | — | US | disclosed |
| US-7884175-B2 | polymerizing one or more monomers containing dihalogen containing substituted biaryls, via a base-induced dehydrohalogenation | MERCK PATENT GMBH (DE) | 2011-02-08 | — | — | US | disclosed |
| EP-1623471-B1 | METHOD FOR CONTROLLING THE MOLECULAR WEIGHT DURING POLY(ARYLENE VINYLENE) SYNTHESIS, AND POLYMERS PRODUCED THEREWITH | MERCK PATENT GMBH (DE) | 2007-05-30 | — | — | EP | disclosed |