Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | CNR2 | P34972 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 2/20 | 0.39 |
| ▸ | NOS3 | P29474 | 1/20 | 0.39 |
| ▸ | NOS1 | P29475 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | LPL | P06858 | 1/20 | 0.36 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL805466 | 0.83 | — | — | |
| SCHEMBL16977554 | 0.79 | TAAR1 (0.50) | KDM4ELMNACYP3A4TSHRRECQL | |
| SCHEMBL5361830 | 0.79 | MAPT (0.55) | KDM4ELMNATSHRHPGDMAPK1 | |
| SCHEMBL12826953 | 0.78 | CCR1 (0.44) | CNR1CNR2KDM4ELMNACYP3A4 | |
| SCHEMBL487201 | 0.78 | KDM4E (0.56) | CNR1CNR2KDM4ELMNACYP3A4 | |
| SCHEMBL13028808 | 0.78 | ESR1 (0.47) | KDM4ECYP3A4NOS2NOS3NOS1 | |
| SCHEMBL5102581 | 0.78 | KDM4E (0.47) | CNR1CNR2KDM4ELMNACYP3A4 | |
| Hydrochloric Acid SCHEMBL6952555 | 0.78 | DRD2 (0.52) | KDM4ELMNACYP3A4TSHRNOS1 | |
| Bromide SCHEMBL2025879 | 0.78 | TAAR1 (0.48) | KDM4ELMNACYP3A4TSHRNOS1 | |
| SCHEMBL6172313 | 0.77 | ALDH1A1 (0.44) | CNR1CNR2KDM4ELMNACYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11192865-B2 | Benzosulfonyl compounds | VIVACE THERAPEUTICS, INC. (US) | 2021-12-07 | — | — | US | disclosed |
| US-11124537-B2 | Inhibitors of glucocorticoid receptor | ORIC PHARMACEUTICALS, INC. (US) | 2021-09-21 | — | — | US | disclosed |
| US-20210017220-A1 | INHIBITORS OF GLUCOCORTICOID RECEPTOR | ORIC PHARMACEUTICALS, INC. | 2021-01-21 | — | — | US | disclosed |
| US-10836789-B2 | Inhibitors of glucocorticoid receptor | ORIC PHARMACEUTICALS, INC. (US) | 2020-11-17 | — | — | US | disclosed |
| US-20190307743-A1 | OPIOID RECEPTOR ANTAGONIST PRODRUGS | NIRSUM LABORATORIES, INC. | 2019-10-10 | — | — | US | disclosed |
| US-10392367-B2 | IRE1 small molecule inhibitors | QUENTIS THERAPEUTICS, INC. (US) | 2019-08-27 | — | — | US | disclosed |
| WO-2016022955-A1 | COMPOUNDS AND METHODS FOR TREATING CANCER | MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH (US) | 2016-02-11 | — | — | WO | disclosed |
| US-20120165309-A1 | HETERO RING DERIVATIVE | ASTELLAS PHARMA INC. (JP) | 2012-06-28 | — | — | US | disclosed |
| US-20100286390-A1 | PYRIDAZINONE COMPOUNDS AND P2X7 RECEPTOR INHIBITORS | NISSAN CHEMICAL INDUSTRIES LIMITED | 2010-11-11 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11124537-B2 | Inhibitors of glucocorticoid receptor | NR3C1, NR3C2, MC2R | CNR1 161/4885CNR2 289/4885KDM4E 3271/4885 |
| US-10392367-B2 | IRE1 small molecule inhibitors | XBP1, ERN2, ERN1 | CNR1 4554/4885CNR2 4665/4885KDM4E 1677/4885 |
| US-11192865-B2 | Benzosulfonyl compounds | YAP1, TEAD2, TEAD1 | CNR1 4091/4885CNR2 4293/4885KDM4E 312/4885 |
| US-20190307743-A1 | OPIOID RECEPTOR ANTAGONIST PRODRUGS | OPRM1, OPRK1, OPRL1 | CNR1 16/4885CNR2 21/4885KDM4E 931/4885 |
| US-20120165309-A1 | HETERO RING DERIVATIVE | IL2, PIK3R2, IL2RA | CNR1 1231/4885CNR2 214/4885KDM4E 3844/4885 |
| US-10836789-B2 | Inhibitors of glucocorticoid receptor | NR3C1, NR3C2, MC2R | CNR1 156/4885CNR2 286/4885KDM4E 3331/4885 |
| US-20100286390-A1 | PYRIDAZINONE COMPOUNDS AND P2X7 RECEPTOR INHIBITORS | P2RY1, P2RX7, P2RX1 | CNR1 79/4885CNR2 128/4885KDM4E 3762/4885 |
| US-20210017220-A1 | INHIBITORS OF GLUCOCORTICOID RECEPTOR | NR3C1, NR3C2, MC2R | CNR1 161/4885CNR2 289/4885KDM4E 3271/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.