Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | CASP7 | P55210 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | GAB1 | Q13480 | 1/20 | 0.38 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | G6PD | P11413 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CCR1 | P32246 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.36 |
| ▸ | CCR4 | P51679 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2740954 | 0.81 | CRHBP (0.45) | CA2SMN1; SMN2GAB1MEN1KMT2A | |
| SCHEMBL13128919 | 0.77 | MEN1 (0.46) | PTGES2TSHRCASP1CASP7SMN1; SMN2 | |
| SCHEMBL13128923 | 0.71 | ALDH1A1 (0.51) | PTGES2TSHRMEN1KMT2AGAA | |
| SCHEMBL13128930 | 0.68 | SMN1; SMN2 (0.47) | PTGES2TSHRSMN1; SMN2HSD17B10HSD11B1 | |
| SCHEMBL13128931 | 0.65 | LMNA (0.47) | PTGES2SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL28920141 | 0.65 | CA2 (0.49) | CA2TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL7592222 | 0.64 | TSHR (0.71) | CA2TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL30557370 | 0.64 | TSHR (0.71) | CA2TSHRSMN1; SMN2MEN1KMT2A | |
| SCHEMBL13128980 | 0.64 | L3MBTL1 (0.50) | SMN1; SMN2HSD17B10MEN1KMT2AGAA | |
| SCHEMBL13128924 | 0.63 | ALDH1A1 (0.64) | TSHRMEN1KMT2ACCR2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | THE GENETICS COMPANY, INC. (CH) | 2010-09-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100249135-A1 | SULFONAMIDES AND THEIR USE AS A MEDICAMENT | BCOR, CBR3, SULT1E1 | CA2 304/4885PTGES2 681/4885TSHR 760/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.