Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.48 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.48 |
| ▸ | CCKBR | P32239 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.42 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.42 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.42 |
| ▸ | CCKAR | P32238 | 2/20 | 0.41 |
| ▸ | GPR139 | Q6DWJ6 | 1/20 | 0.39 |
| ▸ | KDM5A | P29375 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.37 |
| ▸ | DRD2 | P14416 | 1/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | DRD3 | P35462 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13189120 | 0.90 | SIGMAR1 (0.58) | TMEM97SIGMAR1ALDH1A1MEN1GAA | |
| SCHEMBL13691863 | 0.82 | TACR2 (0.49) | TMEM97SIGMAR1ALDH1A1OPRK1 | |
| SCHEMBL13691861 | 0.80 | OPRK1 (0.55) | TMEM97SIGMAR1ALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL13691662 | 0.78 | TMEM97 (0.47) | TMEM97SIGMAR1LMNACYP2C9GPR139 | |
| SCHEMBL13189116 | 0.76 | UTS2R (0.39) | TMEM97SIGMAR1ALDH1A1TSHRDRD2 | |
| SCHEMBL13189113 | 0.76 | UTS2R (0.38) | TMEM97SIGMAR1GPR139DRD2DRD4 | |
| SCHEMBL13689521 | 0.74 | OPRK1 (0.51) | TMEM97SIGMAR1ALDH1A1OPRK1DRD2 | |
| SCHEMBL13190976 | 0.73 | OPRK1 (0.52) | TMEM97SIGMAR1ALDH1A1GPR139OPRK1 | |
| SCHEMBL13691855 | 0.72 | DRD2 (0.45) | ALDH1A1OPRK1DRD2DRD4DRD3 | |
| SCHEMBL13189114 | 0.71 | PIN1 (0.40) | CCKBROPRK1DRD2DRD3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010096854-A1 | METHODS OF MODULATING THE ACTIVITY OF THE MC3 AND/OR MC4 RECEPTORS AND TREATMENT OF CONDITIONS RELATED TO THESE RECEPTORS | MIMETICA PTY LTD (AU) | 2010-09-02 | — | — | WO | disclosed |