Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA9 | Q16790 | 2/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | MMP2 | P08253 | 11/20 | 0.50 |
| ▸ | MMP9 | P14780 | 10/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.45 |
| ▸ | MMP12 | P39900 | 4/20 | 0.44 |
| ▸ | MMP8 | P22894 | 4/20 | 0.41 |
| ▸ | MMP3 | P08254 | 3/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | MMP14 | P50281 | 3/20 | 0.41 |
| ▸ | MMP7 | P09237 | 1/20 | 0.41 |
| ▸ | MMP15 | P51511 | 1/20 | 0.41 |
| ▸ | MMP16 | P51512 | 1/20 | 0.41 |
| ▸ | MMP26 | Q9NRE1 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13201340 | 0.97 | MMP2 (0.53) | CA9CA1CA2MMP2MMP9 | |
| SCHEMBL8319432 | 0.88 | ACHE (0.52) | CA9CA1CA2MMP2MMP9 | |
| SCHEMBL2961151 | 0.88 | ACHE (0.52) | CA9CA1CA2MMP2MMP9 | |
| SCHEMBL8320651 | 0.87 | MMP9 (0.62) | CA9MMP2MMP9MMP12MMP8 | |
| SCHEMBL13480199 | 0.86 | MMP2 (0.49) | CA9MMP2MMP9MMP12MMP8 | |
| SCHEMBL13201330 | 0.86 | MMP8 (0.52) | CA9MMP2MMP9ACHEMMP12 | |
| SCHEMBL16298354 | 0.86 | MMP2 (0.49) | CA9MMP2MMP9MMP12MMP8 | |
| SCHEMBL13201349 | 0.86 | ACHE (0.49) | CA9CA1CA2MMP2ACHE | |
| SCHEMBL8325151 | 0.84 | MMP9 (0.62) | CA9MMP2MMP9MMP12MMP8 | |
| SCHEMBL2965640 | 0.84 | ACHE (0.55) | MMP2MMP9ACHEEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7772270-B2 | Imino acid derivatives as inhibitors of matrix metalloproteinases | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-08-10 | — | — | US | disclosed |
| US-7772270-B2 | Imino acid derivatives as inhibitors of matrix metalloproteinases | SANOFI-AVENTIS DEUTSCHLAND GMBH (DE) | 2010-08-10 | — | — | US | disclosed |
| WO-2004060874-A1 | IMINO ACID DERIVATIVES FOR USE AS INHIBITORS OF MATRIX METALLOPROTEINASES | AVENTIS PHARMA DEUTSCHLAND GMBH (DE) | 2004-07-22 | — | — | WO | disclosed |