SCHEMBL13217015

SCHEMBL13217015

CO[C@@H]1OC(CO)[C@@H](C)C(O)C1N

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 2/20 0.41
▸ FGF1 P05230 1/20 0.38
▸ CA1 P00915 1/20 0.37
▸ CA2 P00918 1/20 0.37
▸ CA9 Q16790 1/20 0.37
▸ MGAM O43451 4/20 0.36
▸ SI P14410 4/20 0.36
▸ LMNA P02545 1/20 0.36
▸ KDM4E B2RXH2 1/20 0.36
▸ ALOX15 P16050 1/20 0.36
▸ PYGB P11216 1/20 0.36
▸ MEN1 O00255 1/20 0.35
▸ LRAT O95237 1/20 0.35
▸ TRPV1 Q8NER1 1/20 0.35
▸ L3MBTL1 Q9Y468 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12019429 1.00 LGALS8 (0.41) LGALS8FGF1CA1CA2CA9
SCHEMBL26878917 1.00 LGALS8 (0.41) LGALS8FGF1CA1CA2CA9
SCHEMBL14748251 1.00 LGALS8 (0.41) LGALS8FGF1CA1CA2CA9
SCHEMBL26878966 1.00 LGALS8 (0.41) LGALS8FGF1CA1CA2CA9
SCHEMBL12917667 1.00 LGALS8 (0.41) LGALS8FGF1CA1CA2CA9
SCHEMBL12589717 1.00 LGALS8 (0.41) LGALS8FGF1CA1CA2CA9
SCHEMBL24980481 1.00 LGALS8 (0.41) LGALS8FGF1CA1CA2CA9
SCHEMBL19718576 0.89 MEN1 (0.46) FGF1LMNAKDM4EALOX15MEN1
SCHEMBL11941427 0.89 MEN1 (0.46) FGF1LMNAKDM4EALOX15MEN1
SCHEMBL13488460 0.89 MEN1 (0.46) FGF1LMNAKDM4EALOX15MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11155647-B2 Water-soluble polysaccharide derivatives, process for their preparation, and their uses JOINTHERAPEUTICS S.R.L. (IT) 2021-10-26 — — US disclosed
US-20210187170-A1 ABSORBABLE IRON-BASED IMPLANTABLE DEVICE BIOTYX MEDICAL (SHENZHEN) CO., LTD. (CN) 2021-06-24 — — US disclosed
US-20200354480-A1 WATER SOLUBLE NITRIC OXIDE-RELEASING POLYGLUCOSAMINES AND USES THEREOF THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL 2020-11-12 — — US disclosed
US-20200297755-A1 PHARMACEUTICAL COMPOSITION FOR TREATING JOINT INFLAMMATION JOINTHERAPEUTICS S.R.L. (IT) 2020-09-24 — — US disclosed
EP-1881009-B1 CHITOSAN DERIVATIVE AND METHOD FOR PRODUCING SAME UNIV NAGOYA NAT UNIV CORP (JP) 2015-01-07 — — EP disclosed
US-7772382-B2 Chitosan derivative and method of producing same NATIONAL UNIVERSITY CORPORATION NAGOYA UNIVERSITY (JP) 2010-08-10 — — US disclosed
US-20090062519-A1 Chitosan Derivative and Method of Producing Same DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2009-03-05 — — US disclosed
EP-1881009-A1 CHITOSAN DERIVATIVE AND METHOD FOR PRODUCING SAME National University Corporation Nagoya University (JP) 2008-01-23 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200297755-A1 PHARMACEUTICAL COMPOSITION FOR TREATING JOINT INFLAMMATION TLR6, TLR3, TLR1 LGALS8 380/4885FGF1 207/4885CA1 1473/4885
US-11155647-B2 Water-soluble polysaccharide derivatives, process for their preparation, and their uses CD44, ALG1, CSGALNACT1 LGALS8 250/4885FGF1 1222/4885CA1 1436/4885
US-20210187170-A1 ABSORBABLE IRON-BASED IMPLANTABLE DEVICE FTH1, SLC40A1, SI LGALS8 257/4885FGF1 1391/4885CA1 71/4885
US-20200354480-A1 WATER SOLUBLE NITRIC OXIDE-RELEASING POLYGLUCOSAMINES AND USES THEREOF NOS3, NOS2, NOS1 LGALS8 80/4885FGF1 2014/4885CA1 1008/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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